Bone tissue engineering (BTE) using scaffolds with growth factors/ stem cells has received some success in clinical trails. Recently, osteogenic scaffolds using absorbable or nonabsorbable biomaterials have being investigated to repair bone defects. Scaffolds can provide the osteoconduction effect as well as a media to trap cells and allow them to proliferate and differentiate. Bioreactors provide a means to uniformly coat the scaffolds with cells and allow cells to proliferate better. Here we describe our work on preclinical animal trials applying the above concept to regenerate bone.
|Title of host publication||Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine|
|Publisher||Pan Stanford Publishing Pte. Ltd.|
|Number of pages||31|
|Publication status||Published - 2012 Jan 31|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)