Effect of scaffolds with bone growth factors on new bone formation

Hae Ryong Song, Swee Hin Teoh, Hak Jun Kim, Ji Hoon Bae, Sung Eun Kim, Young Pil Yun, Muhammad Qasim, Jerry Chan, Zhi Yong Zhang, Chang Wug Oh, Jun Ho Wang

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Bone tissue engineering (BTE) using scaffolds with growth factors/stem cells has received some success in clinical trials. Recently, osteogenic scaffolds using absorbable or nonabsorbable biomaterials have being investigated to repair bone defects. Scaffolds can provide the osteoconduction effect as well as a media to trap cells and allow them to proliferate and differentiate. Bioreactors provide a means to 1114uniformly coat the scaffolds with cells and allow cells to proliferate better. Here we describe our work on preclinical animal trials applying the above concept to regenerate bone.

Original languageEnglish
Title of host publicationHandbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine, 2nd Edition
PublisherPan Stanford Publishing Pte. Ltd.
Pages1113-1173
Number of pages61
ISBN (Electronic)9789814745130
ISBN (Print)9789814745123
DOIs
Publication statusPublished - 2017 Jan 1

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Materials Science(all)

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    Song, H. R., Teoh, S. H., Kim, H. J., Bae, J. H., Kim, S. E., Yun, Y. P., Qasim, M., Chan, J., Zhang, Z. Y., Oh, C. W., & Wang, J. H. (2017). Effect of scaffolds with bone growth factors on new bone formation. In Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine, 2nd Edition (pp. 1113-1173). Pan Stanford Publishing Pte. Ltd.. https://doi.org/10.1201/9781315364698