Effect of Stenting Strategy on the Outcome in Patients with Non-Left Main Bifurcation Lesions

Yongwhan Lim, Min Chul Kim, Youngkeun Ahn, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Hyeon Cheol Gwon, Hyo Soo Kim, Seung Woon Rha, Jung Han Yoon, Yangsoo Jang, Seung Jea Tahk, Ki Bae Seung

Research output: Contribution to journalArticlepeer-review

Abstract

Previous studies have not compared outcomes between different percutaneous coronary intervention (PCI) strategies and lesion locations in non-left main (LM) bifurcation lesions. We enrolled 2044 patients from a multicenter registry with an LAD bifurcation lesion (n = 1551) or non-LAD bifurcation lesion (n = 493). The primary outcome was target lesion failure (TLF), a composite of cardiac death, myocardial infarction, and target lesion revascularization (TLR). During a median follow-up period of 38 months, non-LAD bifurcation lesions treated with the two-stent strategy, compared with the one-stent strategy, were associated with more frequent TLF (20.7% vs. 6.3%, p < 0.01), TLR (16.7% vs. 4.7%, p < 0.01), and target vessel revascularization (TVR; 18.2% vs. 6.3%, p < 0.01). There was no significant difference in outcome among LAD bifurcation lesions treated with different PCI strategies. The two-stent strategy was associated with a higher risk of TLF (adjusted HR 4.34, CI 1.93–9.76, p < 0.01), TLR (adjusted HR 4.30, CI 1.64–11.27, p < 0.01), and TVR (adjusted HR 5.07, CI 1.69–9.74, p < 0.01) in the non-LAD bifurcation lesions. The planned one-stent strategy is preferable to the two-stent strategy for the treatment of non-LAD bifurcation lesions.

Original languageEnglish
Article number5658
JournalJournal of Clinical Medicine
Volume11
Issue number19
DOIs
Publication statusPublished - 2022 Oct
Externally publishedYes

Keywords

  • Bifurcation
  • elective two stent
  • non-left main bifurcation
  • percutaneous coronary intervention
  • provisional one-stent

ASJC Scopus subject areas

  • Medicine(all)

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