Effect of upper airway surgery on heart rate variability in patients with obstructive sleep apnoea syndrome

Ji Ho Choi, Jong Sook Yi, Seung Hoon Lee, Cheon Sik Kim, Tae Hoon Kim, Heung Man Lee, Bong Jae Lee, Sang Hag Lee, Yoo Sam Chung

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

To determine whether surgery influences cardiovascular autonomic modulation in obstructive sleep apnoea syndrome (OSAS), the present study was performed to evaluate the effect of upper airway (UA) surgery on heart rate variability (HRV) using frequency domain analysis for patient groups who have had either successful or unsuccessful surgery. We compared body mass index (BMI), polysomnographic [apnoea index (AI), apnoea-hypopnoea index (AHI), minimum SaO 2] and HRV [very low frequency (VLF) power, low frequency (LF) power, high frequency (HF) power, HF/LF ratio, LFnu=LF/(LF+HF), HFnu=HF/(LF+HF)] parameters between the unsuccessful (n=14) and successful (n=22) surgical groups before and after UA surgery. Significant changes were observed for the successful patient group with respect to mean AI (from 29.1±21.3 to 2.0±3.2 events h -1, P<0.001), AHI (from 38.6±20.0 to 5.6±5.1 eventsh -1, P<0.001), minimum SaO 2 (from 73.3±12.7 to 86.3±6.5%, P<0.001), VLF power (from 25599±12906 to 20014±9839ms 2, P=0.013), LF power (from 17293±7278 to 14155±4980ms 2, P=0.016), LFnu (from 0.700±0.104 to 0.646±0.128, P=0.031) and HFnu (from 0.300±0.104 to 0.354±0.128, P=0.031); however, mean BMI, HF power and LF/HF ratio did not change significantly after UA surgery. No significant changes were observed in the unsuccessful surgical group. Successful UA surgery may improve cardiac sympathetic and parasympathetic modulation in patients with OSAS.

Original languageEnglish
Pages (from-to)316-321
Number of pages6
JournalJournal of Sleep Research
Volume21
Issue number3
DOIs
Publication statusPublished - 2012 Jun

Keywords

  • Autonomic function
  • Obstructive sleep apnoea
  • Polysomnography
  • Surgery

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Effect of upper airway surgery on heart rate variability in patients with obstructive sleep apnoea syndrome'. Together they form a unique fingerprint.

  • Cite this