Effective methods to improve the biocompatibility of poly (dimethylsiloxane)

Joong Yull Park, Chang Mo Hwang, Sang Hoon Lee

Research output: Contribution to journalArticle

4 Citations (Scopus)


Poly (dimethylsiloxane) (PDMS) has become one of the popular materials in the field of bio-related microfluidic systems, and has been used for various biological assays. While the material is known to be biocompatible in general, it also has been reported that the attachment and survival rate of cells are limited on a PDMS substrate. In this paper, a simple and relevant method to improve the biocompatibility of PDMS is proposed; the effects of various treatments using ethanol, water, and boiling-water were evaluated. The results show that the boiling-water treatment is the most appropriate, time saving, and simple method to improve the biocompatibility of PDMS.

Original languageEnglish
Pages (from-to)39-43
Number of pages5
JournalBiochip Journal
Issue number1
Publication statusPublished - 2008 Dec 1



  • Biocompatibility
  • Fibroblast
  • Microfluidic chip
  • PDMS

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering
  • Electrical and Electronic Engineering

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