Effects of alginate microencapsulation on the fibrinolytic activity of fermented soybean paste (Cheonggukjang) extract

J. A. Ko, S. Y. Koo, Hyun Jin Park

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Alginate microparticles were prepared to evaluate the effect on the fibrinolytic activity of Korean fermented soybean paste, Cheonggukjang (CGJ). The mean diameter of microparticles was 110.37 μm and the microparticles had generally spherical and some wrinkled surfaces. The fibrinolytic activities of encapsulated and non-encapsulated CGJ extract were measured at various ranges of pH and temperature. When non-encapsulated CGJ extract was exposed to simulated gastric juice of pH 2.0, the fibrinolytic activity was rapidly reduced. However, fibrinolytic activity of encapsulated CGJ extract (14.27 units) was significantly higher than that of non-encapsulated CGJ extract (4.15 units). The fibrinolytic activity of non-encapsulated CGJ extract decreased rapidly with increased temperature, but stability of fibrinolytic activity of encapsulated CGJ was improved under high temperature conditions. These results indicate that the microencapsulation technique is an effective tool to protect the fibrinolytic activity of CGJ extract from ingestion and heating effects.

Original languageEnglish
Pages (from-to)921-924
Number of pages4
JournalFood Chemistry
Volume111
Issue number4
DOIs
Publication statusPublished - 2008 Dec 15

Fingerprint

Microencapsulation
microencapsulation
Drug Compounding
alginates
Ointments
Soybeans
soybeans
Temperature
extracts
Gastric Juice
Heating
Thermodynamic properties
Eating
gastric juice
temperature
alginic acid
ingestion
heat

Keywords

  • Alginate microparticle
  • Cheonggukjang
  • Fibrinolytic activity

ASJC Scopus subject areas

  • Food Science

Cite this

Effects of alginate microencapsulation on the fibrinolytic activity of fermented soybean paste (Cheonggukjang) extract. / Ko, J. A.; Koo, S. Y.; Park, Hyun Jin.

In: Food Chemistry, Vol. 111, No. 4, 15.12.2008, p. 921-924.

Research output: Contribution to journalArticle

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N2 - Alginate microparticles were prepared to evaluate the effect on the fibrinolytic activity of Korean fermented soybean paste, Cheonggukjang (CGJ). The mean diameter of microparticles was 110.37 μm and the microparticles had generally spherical and some wrinkled surfaces. The fibrinolytic activities of encapsulated and non-encapsulated CGJ extract were measured at various ranges of pH and temperature. When non-encapsulated CGJ extract was exposed to simulated gastric juice of pH 2.0, the fibrinolytic activity was rapidly reduced. However, fibrinolytic activity of encapsulated CGJ extract (14.27 units) was significantly higher than that of non-encapsulated CGJ extract (4.15 units). The fibrinolytic activity of non-encapsulated CGJ extract decreased rapidly with increased temperature, but stability of fibrinolytic activity of encapsulated CGJ was improved under high temperature conditions. These results indicate that the microencapsulation technique is an effective tool to protect the fibrinolytic activity of CGJ extract from ingestion and heating effects.

AB - Alginate microparticles were prepared to evaluate the effect on the fibrinolytic activity of Korean fermented soybean paste, Cheonggukjang (CGJ). The mean diameter of microparticles was 110.37 μm and the microparticles had generally spherical and some wrinkled surfaces. The fibrinolytic activities of encapsulated and non-encapsulated CGJ extract were measured at various ranges of pH and temperature. When non-encapsulated CGJ extract was exposed to simulated gastric juice of pH 2.0, the fibrinolytic activity was rapidly reduced. However, fibrinolytic activity of encapsulated CGJ extract (14.27 units) was significantly higher than that of non-encapsulated CGJ extract (4.15 units). The fibrinolytic activity of non-encapsulated CGJ extract decreased rapidly with increased temperature, but stability of fibrinolytic activity of encapsulated CGJ was improved under high temperature conditions. These results indicate that the microencapsulation technique is an effective tool to protect the fibrinolytic activity of CGJ extract from ingestion and heating effects.

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