TY - JOUR
T1 - Effects of dietary fibers and prebiotics in adiposity regulation via modulation of gut microbiota
AU - Rivera-Piza, Adriana
AU - Lee, Sung Joon
N1 - Funding Information:
This work was carried out with the support of the ‘Cooperative Research Program for Agriculture Science & Technology Development (Project No. PJ011253042018)’, Rural Development Administration (RDA), Republic of Korea and by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (NRF-2018R1A4A1022589).
Publisher Copyright:
© 2020, The Author(s).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - The microbiota is indispensable for human health and the regulation of various body functions, including energy metabolism. The harmonic crosstalk between the microbiota and the intestinal epithelial barrier determines gut homeostasis and health status in the healthy subject. Obesity and type 2 diabetes risk are, to some extent, explained by alterations in the microbiota. Since recent data indicate that the population of gut microorganisms can influence nutrient absorption and energy storage thus prevalence on obesity and metabolic disorders. Moreover, metabolic disease conditions, such as obesity, may be stimulated by genetic, environmental factors and by pathways that link metabolism with the immune system. On the basis of the above considerations, this review compiles the current results obtained in recent studies indicating the gut microbiota contribution to obesity development.
AB - The microbiota is indispensable for human health and the regulation of various body functions, including energy metabolism. The harmonic crosstalk between the microbiota and the intestinal epithelial barrier determines gut homeostasis and health status in the healthy subject. Obesity and type 2 diabetes risk are, to some extent, explained by alterations in the microbiota. Since recent data indicate that the population of gut microorganisms can influence nutrient absorption and energy storage thus prevalence on obesity and metabolic disorders. Moreover, metabolic disease conditions, such as obesity, may be stimulated by genetic, environmental factors and by pathways that link metabolism with the immune system. On the basis of the above considerations, this review compiles the current results obtained in recent studies indicating the gut microbiota contribution to obesity development.
KW - Energy metabolism
KW - Gut microbiota
KW - Obesity
KW - Prebiotics
UR - http://www.scopus.com/inward/record.url?scp=85077522135&partnerID=8YFLogxK
U2 - 10.1186/s13765-019-0482-9
DO - 10.1186/s13765-019-0482-9
M3 - Review article
AN - SCOPUS:85077522135
SN - 2468-0834
VL - 63
JO - Applied Biological Chemistry
JF - Applied Biological Chemistry
IS - 1
M1 - 2
ER -
