Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals

Sang Hee Kim, Hyun Jung Han, Hyeon Min Ahn, Shin Ah Kim, Sang Eun Kim

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.

Original languageEnglish
Pages (from-to)256-260
Number of pages5
JournalNeuroscience Research
Volume74
Issue number3-4
DOIs
Publication statusPublished - 2012 Dec 1

Fingerprint

Transcranial Magnetic Stimulation
Task Performance and Analysis
Prefrontal Cortex
Reaction Time
Young Adult
Therapeutics

Keywords

  • Aging
  • Dorsolateral prefrontal cortex
  • Inhibitory
  • RTMS
  • Stroop

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals. / Kim, Sang Hee; Han, Hyun Jung; Ahn, Hyeon Min; Kim, Shin Ah; Kim, Sang Eun.

In: Neuroscience Research, Vol. 74, No. 3-4, 01.12.2012, p. 256-260.

Research output: Contribution to journalArticle

Kim, Sang Hee ; Han, Hyun Jung ; Ahn, Hyeon Min ; Kim, Shin Ah ; Kim, Sang Eun. / Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals. In: Neuroscience Research. 2012 ; Vol. 74, No. 3-4. pp. 256-260.
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