Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals

Sang Hee Kim; Hyun Jung Han; Hyeon Min Ahn; Shin Ah Kim; Sang Eun Kim

doi:10.1016/j.neures.2012.08.008

Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals

Sang Hee Kim, Hyun Jung Han, Hyeon Min Ahn, Shin Ah Kim, Sang Eun Kim

Department of Brain and Cognitive Engineering

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.

Original language	English
Pages (from-to)	256-260
Number of pages	5
Journal	Neuroscience Research
Volume	74
Issue number	3-4
DOIs	https://doi.org/10.1016/j.neures.2012.08.008
Publication status	Published - 2012 Dec

Keywords

Aging
Dorsolateral prefrontal cortex
Inhibitory
RTMS
Stroop

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/j.neures.2012.08.008

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title = "Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals",

abstract = "Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.",

keywords = "Aging, Dorsolateral prefrontal cortex, Inhibitory, RTMS, Stroop",

author = "Kim, {Sang Hee} and Han, {Hyun Jung} and Ahn, {Hyeon Min} and Kim, {Shin Ah} and Kim, {Sang Eun}",

note = "Funding Information: This work was supported by the National Research Foundation of Korea (NRF) grants funded by the Ministry of Education, Science and Technology, the Republic of Korea (Nos. 2010-0005689 and 2012R1A2A2A01012159 ).",

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doi = "10.1016/j.neures.2012.08.008",

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AU - Kim, Sang Hee

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AU - Ahn, Hyeon Min

AU - Kim, Shin Ah

AU - Kim, Sang Eun

N1 - Funding Information: This work was supported by the National Research Foundation of Korea (NRF) grants funded by the Ministry of Education, Science and Technology, the Republic of Korea (Nos. 2010-0005689 and 2012R1A2A2A01012159 ).

PY - 2012/12

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N2 - Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.

AB - Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.

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Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals

Abstract

Keywords

ASJC Scopus subject areas

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