Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals

Sang Hee Kim, Hyun Jung Han, Hyeon Min Ahn, Shin Ah Kim, Sang Eun Kim

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)


Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.

Original languageEnglish
Pages (from-to)256-260
Number of pages5
JournalNeuroscience Research
Issue number3-4
Publication statusPublished - 2012 Dec


  • Aging
  • Dorsolateral prefrontal cortex
  • Inhibitory
  • RTMS
  • Stroop

ASJC Scopus subject areas

  • Neuroscience(all)


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