Abstract
Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.
| Original language | English |
|---|---|
| Pages (from-to) | 256-260 |
| Number of pages | 5 |
| Journal | Neuroscience Research |
| Volume | 74 |
| Issue number | 3-4 |
| DOIs | |
| Publication status | Published - 2012 Dec 1 |
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Keywords
- Aging
- Dorsolateral prefrontal cortex
- Inhibitory
- RTMS
- Stroop
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals. / Kim, Sang Hee; Han, Hyun Jung; Ahn, Hyeon Min; Kim, Shin Ah; Kim, Sang Eun.
In: Neuroscience Research, Vol. 74, No. 3-4, 01.12.2012, p. 256-260.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals
AU - Kim, Sang Hee
AU - Han, Hyun Jung
AU - Ahn, Hyeon Min
AU - Kim, Shin Ah
AU - Kim, Sang Eun
PY - 2012/12/1
Y1 - 2012/12/1
N2 - Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.
AB - Previous evidence suggests that high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) improves inhibitory control in healthy young adults. Little is known as to whether HF-rTMS would show similar facilitation effects in older adults undergoing normal aging. We recruited 16 healthy elderly adults and randomly assigned them to either a 10. Hz HF-rTMS or sham stimulation group. Five daily stimulation sessions over the left dorsolateral prefrontal cortex were given to each participant. Changes in inhibitory control were assessed using a modified Stroop task. Participants performed the Stroop task twice, 1 day before and after the five daily stimulations. We found that participants in the active HF-rTMS stimulation group showed improved performance in reaction time during incongruent trials (i.e. those with distracting information) after HF-rTMS treatment compared with pre-treatment trials. To the best of our knowledge, this study is one of the first studies demonstrating that daily HF-rTMS can improve attentional control in normally aging individuals.
KW - Aging
KW - Dorsolateral prefrontal cortex
KW - Inhibitory
KW - RTMS
KW - Stroop
UR - http://www.scopus.com/inward/record.url?scp=84871931009&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871931009&partnerID=8YFLogxK
U2 - 10.1016/j.neures.2012.08.008
DO - 10.1016/j.neures.2012.08.008
M3 - Article
C2 - 22974554
AN - SCOPUS:84871931009
VL - 74
SP - 256
EP - 260
JO - Neuroscience Research
JF - Neuroscience Research
SN - 0168-0102
IS - 3-4
ER -