TY - JOUR
T1 - Effects of foot complications in patients with Type 2 diabetes mellitus on public healthcare
T2 - An analysis based on the Korea National Diabetes Program Cohort
AU - KNDP study investigators
AU - Park, So Young
AU - Rhee, Sang Youl
AU - Chon, Suk
AU - Ahn, Kyu Jeung
AU - Kim, Sung Hoon
AU - Baik, Sei Hyun
AU - Park, Yongsoo
AU - Nam, Moon Suk
AU - Lee, Kwan Woo
AU - Woo, Jeong taek
AU - Chun, Ki Hong
AU - Kim, Young Seol
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Aim Diabetes mellitus (DM) patients are susceptible to foot injury or foot diseases such as diabetic foot and peripheral arterial disease. Although these conditions are considered important, few studies have investigated them in detail. Therefore, we investigated the epidemiology of diabetic foot complications (DFC) with respect to the effects on the public healthcare system. Methods We evaluated the incidence, clinical characteristics, health service utilization frequency and medical expenses of DFC in type 2 DM patients in the Korea National Diabetes Program (KNDP), the largest multi-center, prospective cohort in Korea (n = 4405). To determine precise outcomes, we used national representative databases, including claims data from the Health Insurance Review & Assessment Service of Korea. Results During a median follow-up period of 3.30 years, 528 patients (12.0%) were newly diagnosed with DFC at an incidence rate of 43.02 cases per 1000 person-years. The patients with DFC were significantly older than patients without DFC, but other clinical characteristics were similar between the two groups. The patients with DFC had more hospital visits (p < 0.001), longer duration of hospitalization (p < 0.001), and increased expenses (p < 0.001) compared to patients without DFC. After multiple adjustments, the differences in number of hospital visits and medical expenses were consistent. In a before and after comparison within the DFC group, all three variables increased significantly after the onset of DFC (p < 0.001). Conclusions DFC were significantly associated with poor clinical outcomes and caused a substantial burden to the national healthcare system in Korea. Therefore, intervention to prevent DFC is important.
AB - Aim Diabetes mellitus (DM) patients are susceptible to foot injury or foot diseases such as diabetic foot and peripheral arterial disease. Although these conditions are considered important, few studies have investigated them in detail. Therefore, we investigated the epidemiology of diabetic foot complications (DFC) with respect to the effects on the public healthcare system. Methods We evaluated the incidence, clinical characteristics, health service utilization frequency and medical expenses of DFC in type 2 DM patients in the Korea National Diabetes Program (KNDP), the largest multi-center, prospective cohort in Korea (n = 4405). To determine precise outcomes, we used national representative databases, including claims data from the Health Insurance Review & Assessment Service of Korea. Results During a median follow-up period of 3.30 years, 528 patients (12.0%) were newly diagnosed with DFC at an incidence rate of 43.02 cases per 1000 person-years. The patients with DFC were significantly older than patients without DFC, but other clinical characteristics were similar between the two groups. The patients with DFC had more hospital visits (p < 0.001), longer duration of hospitalization (p < 0.001), and increased expenses (p < 0.001) compared to patients without DFC. After multiple adjustments, the differences in number of hospital visits and medical expenses were consistent. In a before and after comparison within the DFC group, all three variables increased significantly after the onset of DFC (p < 0.001). Conclusions DFC were significantly associated with poor clinical outcomes and caused a substantial burden to the national healthcare system in Korea. Therefore, intervention to prevent DFC is important.
KW - Diabetes complications
KW - Diabetes mellitus, type 2
KW - Epidemiology
KW - Korea
KW - Peripheral vascular diseases
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=84997079019&partnerID=8YFLogxK
U2 - 10.1016/j.jdiacomp.2016.06.024
DO - 10.1016/j.jdiacomp.2016.06.024
M3 - Article
C2 - 27445007
AN - SCOPUS:84997079019
VL - 31
SP - 375
EP - 380
JO - Journal of Diabetes and its Complications
JF - Journal of Diabetes and its Complications
SN - 1056-8727
IS - 2
ER -