Effects of gadoxetic acid on image quality of arterial multiphase magnetic resonance imaging of liver

comparison study with gadoteric acid-enhanced MRI

Ki Choon Sim, Beomjin Park, Na Yeon Han, Deuk Jae Sung, Min Ju Kim, Yeo Eun Han

Research output: Contribution to journalArticle

Abstract

Purpose: To compare the effects of gadoxetic acid and gadoteric acid on the image quality of single-breath-hold, triple (first, second, and third) arterial hepatic magnetic resonance imaging (MRI). Methods: Two hundred and eleven patients were divided into two groups according to the contrast materials used (gadoxetic acid, 108 patients and gadoteric acid, 103 patients). All 3.0-T MR examinations included triple arterial phase acquisition using the 4D enhanced T1-weighted high-resolution isotropic volume examination (eTHRIVE) keyhole technique. The image qualities of the pre-contrast and triple arterial phases were assessed in terms of image artifacts, sharpness of the intrahepatic vessel and liver edge, and overall image quality with a 5-point scale for qualitative analysis. Results: The image quality of gadoxetic acid-enhanced liver MRI in the triple arterial phases was significantly degraded compared with that of gadoteric acid-enhanced liver MRI, although better image scores were observed in the pre-contrast images in the gadoxetic acid group (P < 0.001). The overall image quality gradually improved from the first to the third arterial phases in both groups (P < 0.003). Conclusions: Intravenous gadoxetic acid could have a detrimental effect on image quality of triple arterial phase MRI with the 4D eTHRIVE Keyhole technique. The third arterial phase images had the best image qualities; thus, they could be used as key scans.

Original languageEnglish
JournalAbdominal Radiology
DOIs
Publication statusAccepted/In press - 2019 Jan 1

Fingerprint

Magnetic Resonance Imaging
Acids
Liver
Artifacts
Contrast Media
gadolinium ethoxybenzyl DTPA

Keywords

  • Artifacts
  • Contrast media
  • Gd-EOB-DTPA
  • Image quality
  • Liver
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

Cite this

@article{caf3af274952446ca0e530c704fd61d8,
title = "Effects of gadoxetic acid on image quality of arterial multiphase magnetic resonance imaging of liver: comparison study with gadoteric acid-enhanced MRI",
abstract = "Purpose: To compare the effects of gadoxetic acid and gadoteric acid on the image quality of single-breath-hold, triple (first, second, and third) arterial hepatic magnetic resonance imaging (MRI). Methods: Two hundred and eleven patients were divided into two groups according to the contrast materials used (gadoxetic acid, 108 patients and gadoteric acid, 103 patients). All 3.0-T MR examinations included triple arterial phase acquisition using the 4D enhanced T1-weighted high-resolution isotropic volume examination (eTHRIVE) keyhole technique. The image qualities of the pre-contrast and triple arterial phases were assessed in terms of image artifacts, sharpness of the intrahepatic vessel and liver edge, and overall image quality with a 5-point scale for qualitative analysis. Results: The image quality of gadoxetic acid-enhanced liver MRI in the triple arterial phases was significantly degraded compared with that of gadoteric acid-enhanced liver MRI, although better image scores were observed in the pre-contrast images in the gadoxetic acid group (P < 0.001). The overall image quality gradually improved from the first to the third arterial phases in both groups (P < 0.003). Conclusions: Intravenous gadoxetic acid could have a detrimental effect on image quality of triple arterial phase MRI with the 4D eTHRIVE Keyhole technique. The third arterial phase images had the best image qualities; thus, they could be used as key scans.",
keywords = "Artifacts, Contrast media, Gd-EOB-DTPA, Image quality, Liver, Magnetic resonance imaging",
author = "Sim, {Ki Choon} and Beomjin Park and Han, {Na Yeon} and Sung, {Deuk Jae} and Kim, {Min Ju} and Han, {Yeo Eun}",
year = "2019",
month = "1",
day = "1",
doi = "10.1007/s00261-019-02202-0",
language = "English",
journal = "Abdominal Radiology",
issn = "2366-004X",
publisher = "Springer New York",

}

TY - JOUR

T1 - Effects of gadoxetic acid on image quality of arterial multiphase magnetic resonance imaging of liver

T2 - comparison study with gadoteric acid-enhanced MRI

AU - Sim, Ki Choon

AU - Park, Beomjin

AU - Han, Na Yeon

AU - Sung, Deuk Jae

AU - Kim, Min Ju

AU - Han, Yeo Eun

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Purpose: To compare the effects of gadoxetic acid and gadoteric acid on the image quality of single-breath-hold, triple (first, second, and third) arterial hepatic magnetic resonance imaging (MRI). Methods: Two hundred and eleven patients were divided into two groups according to the contrast materials used (gadoxetic acid, 108 patients and gadoteric acid, 103 patients). All 3.0-T MR examinations included triple arterial phase acquisition using the 4D enhanced T1-weighted high-resolution isotropic volume examination (eTHRIVE) keyhole technique. The image qualities of the pre-contrast and triple arterial phases were assessed in terms of image artifacts, sharpness of the intrahepatic vessel and liver edge, and overall image quality with a 5-point scale for qualitative analysis. Results: The image quality of gadoxetic acid-enhanced liver MRI in the triple arterial phases was significantly degraded compared with that of gadoteric acid-enhanced liver MRI, although better image scores were observed in the pre-contrast images in the gadoxetic acid group (P < 0.001). The overall image quality gradually improved from the first to the third arterial phases in both groups (P < 0.003). Conclusions: Intravenous gadoxetic acid could have a detrimental effect on image quality of triple arterial phase MRI with the 4D eTHRIVE Keyhole technique. The third arterial phase images had the best image qualities; thus, they could be used as key scans.

AB - Purpose: To compare the effects of gadoxetic acid and gadoteric acid on the image quality of single-breath-hold, triple (first, second, and third) arterial hepatic magnetic resonance imaging (MRI). Methods: Two hundred and eleven patients were divided into two groups according to the contrast materials used (gadoxetic acid, 108 patients and gadoteric acid, 103 patients). All 3.0-T MR examinations included triple arterial phase acquisition using the 4D enhanced T1-weighted high-resolution isotropic volume examination (eTHRIVE) keyhole technique. The image qualities of the pre-contrast and triple arterial phases were assessed in terms of image artifacts, sharpness of the intrahepatic vessel and liver edge, and overall image quality with a 5-point scale for qualitative analysis. Results: The image quality of gadoxetic acid-enhanced liver MRI in the triple arterial phases was significantly degraded compared with that of gadoteric acid-enhanced liver MRI, although better image scores were observed in the pre-contrast images in the gadoxetic acid group (P < 0.001). The overall image quality gradually improved from the first to the third arterial phases in both groups (P < 0.003). Conclusions: Intravenous gadoxetic acid could have a detrimental effect on image quality of triple arterial phase MRI with the 4D eTHRIVE Keyhole technique. The third arterial phase images had the best image qualities; thus, they could be used as key scans.

KW - Artifacts

KW - Contrast media

KW - Gd-EOB-DTPA

KW - Image quality

KW - Liver

KW - Magnetic resonance imaging

UR - http://www.scopus.com/inward/record.url?scp=85072039719&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85072039719&partnerID=8YFLogxK

U2 - 10.1007/s00261-019-02202-0

DO - 10.1007/s00261-019-02202-0

M3 - Article

JO - Abdominal Radiology

JF - Abdominal Radiology

SN - 2366-004X

ER -