Effects of Lactobacillus acidophilus 43121 and a mixture of Lactobacillus casei and Bifidobacterium longum on the serum cholesterol level and fecal sterol excretion in hypercholesterolemia-induced pigs

Yoo Heon Park, Jong Gun Kim, Young Won Shin, Hyung Soo Kim, Young Jun Kim, Taehoon Chun, Sae Hun Kim, Kwang Youn Whang

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The hypocholesterolemic effects of Lactobacillus acidophilus 43121 (43121) and a mixture of Lactobacillus casei and Bifidobacterium longum (MIX) were studied in hypercholesterolemia-induced pigs. Serum total cholesterol was decreased by supplementation of either 43121 or MIX, although, high-density lipoprotein cholesterol was not changed. The hypocholesterolemic effect of 43121 and MIX was mainly due to bile acid dehydroxylation, this effect being supplementation-time dependent.

Original languageEnglish
Pages (from-to)595-600
Number of pages6
JournalBioscience, Biotechnology and Biochemistry
Volume72
Issue number2
DOIs
Publication statusPublished - 2008 Mar 13

Fingerprint

Lactobacillus acidophilus
Lactobacillus casei
Bifidobacterium longum
cholesteremic effect
hypercholesterolemia
Cholesterol
Sterols
Hypercholesterolemia
Bile Acids and Salts
sterols
HDL Cholesterol
Swine
excretion
cholesterol
Lipoproteins
swine
bile acids
Serum
high density lipoprotein cholesterol
Acids

Keywords

  • Cholesterol
  • Fecal sterol
  • Hypocholesterolemic effect
  • Lactic acid bacteria
  • Pig

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Food Science

Cite this

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abstract = "The hypocholesterolemic effects of Lactobacillus acidophilus 43121 (43121) and a mixture of Lactobacillus casei and Bifidobacterium longum (MIX) were studied in hypercholesterolemia-induced pigs. Serum total cholesterol was decreased by supplementation of either 43121 or MIX, although, high-density lipoprotein cholesterol was not changed. The hypocholesterolemic effect of 43121 and MIX was mainly due to bile acid dehydroxylation, this effect being supplementation-time dependent.",
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T1 - Effects of Lactobacillus acidophilus 43121 and a mixture of Lactobacillus casei and Bifidobacterium longum on the serum cholesterol level and fecal sterol excretion in hypercholesterolemia-induced pigs

AU - Park, Yoo Heon

AU - Kim, Jong Gun

AU - Shin, Young Won

AU - Kim, Hyung Soo

AU - Kim, Young Jun

AU - Chun, Taehoon

AU - Kim, Sae Hun

AU - Whang, Kwang Youn

PY - 2008/3/13

Y1 - 2008/3/13

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AB - The hypocholesterolemic effects of Lactobacillus acidophilus 43121 (43121) and a mixture of Lactobacillus casei and Bifidobacterium longum (MIX) were studied in hypercholesterolemia-induced pigs. Serum total cholesterol was decreased by supplementation of either 43121 or MIX, although, high-density lipoprotein cholesterol was not changed. The hypocholesterolemic effect of 43121 and MIX was mainly due to bile acid dehydroxylation, this effect being supplementation-time dependent.

KW - Cholesterol

KW - Fecal sterol

KW - Hypocholesterolemic effect

KW - Lactic acid bacteria

KW - Pig

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