Effects of Lactobacillus acidophilus 43121 and a mixture of Lactobacillus casei and Bifidobacterium longum on the serum cholesterol level and fecal sterol excretion in hypercholesterolemia-induced pigs

Yoo Heon Park, Jong Gun Kim, Young Won Shin, Hyung Soo Kim, Young Jun Kim, Taehoon Chun, Sae Hun Kim, Kwang Youn Whang

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Abstract

The hypocholesterolemic effects of Lactobacillus acidophilus 43121 (43121) and a mixture of Lactobacillus casei and Bifidobacterium longum (MIX) were studied in hypercholesterolemia-induced pigs. Serum total cholesterol was decreased by supplementation of either 43121 or MIX, although, high-density lipoprotein cholesterol was not changed. The hypocholesterolemic effect of 43121 and MIX was mainly due to bile acid dehydroxylation, this effect being supplementation-time dependent.

Original languageEnglish
Pages (from-to)595-600
Number of pages6
JournalBioscience, Biotechnology and Biochemistry
Volume72
Issue number2
DOIs
Publication statusPublished - 2008 Mar 13

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Keywords

  • Cholesterol
  • Fecal sterol
  • Hypocholesterolemic effect
  • Lactic acid bacteria
  • Pig

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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