Effects of physical activity and aerobic exercise capacity on aortic stiffness in patients with untreated hypertension

Sang Hoon Na, Yong Seok Kim, Jun Ho Bae, Deuk Young Nah, Young Kwon Kim, Myoung Mook Lee, Hae-Young Kim, Moo Yong Rhee

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background and Objectives: High aerobic exercise capacity and sport-related physical activity are reported to be inversely associated with arterial stiffness in healthy young adults. However, it is unknown whether increased physical activity and/or high aerobic exercise capacity attenuate arterial stiffness in patients with untreated hypertension. Subjects and Methods: We studied subjects with never-treated hypertension {n=84 (55 males); mean age ± SD, 49±7 years; age range, 36-65 years}. We excluded subjects with a history of diabetes, angina, myocardial infarction, major arrhythmia, or cerebrovascular diseases and those who were taking any cardiovascular medications, including lipid-lowering agents. Carotid intima-media thickness (IMT) and heart-femoral pulse wave velocity (hfPWV) were measured before exercise testing was performed. Physical activity was estimated using a modified Baecke questionnaire. Aerobic exercise capacity was measured with maximal cardiopulmonary exercise testing (maximum oxygen uptake, Vo2max). Results: Linear regression analysis showed a significant inverse correlation between sport-index and hfPWV (r=-0.404; p<0.001), which multiple linear regression analysis showed to be independent of the individual variables of age, gender, body mass index, mean arterial pressure, total cholesterol, fasting blood glucose, and heart rate (beta=-0.277; p=0.004). However, the work- and leisure-indices and Vo2max were not associated with hfPWV (p> 0.05). Carotid IMT was not associated with physical activity indices or Vo2max. Conclusion: In patients with untreated hypertension, increased sport activity was associated with lower aortic stiffness, but high aerobic exercise capacity was not. These results suggest that regular daily exercise, but not exercise capacity, is an important determinant of aortic stiffness in patients with untreated hypertension.

Original languageEnglish
Pages (from-to)52-56
Number of pages5
JournalKorean Circulation Journal
Volume39
Issue number2
DOIs
Publication statusPublished - 2009 Feb 1
Externally publishedYes

Fingerprint

Vascular Stiffness
Exercise
Hypertension
Sports
Carotid Intima-Media Thickness
Pulse Wave Analysis
Thigh
Cerebrovascular Disorders
Cardiac Arrhythmias
Young Adult
Linear Models
Myocardial Infarction
Regression Analysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Internal Medicine

Cite this

Effects of physical activity and aerobic exercise capacity on aortic stiffness in patients with untreated hypertension. / Na, Sang Hoon; Kim, Yong Seok; Bae, Jun Ho; Nah, Deuk Young; Kim, Young Kwon; Lee, Myoung Mook; Kim, Hae-Young; Rhee, Moo Yong.

In: Korean Circulation Journal, Vol. 39, No. 2, 01.02.2009, p. 52-56.

Research output: Contribution to journalArticle

Na, Sang Hoon ; Kim, Yong Seok ; Bae, Jun Ho ; Nah, Deuk Young ; Kim, Young Kwon ; Lee, Myoung Mook ; Kim, Hae-Young ; Rhee, Moo Yong. / Effects of physical activity and aerobic exercise capacity on aortic stiffness in patients with untreated hypertension. In: Korean Circulation Journal. 2009 ; Vol. 39, No. 2. pp. 52-56.
@article{4a33f77576d5460893f23666d27a9242,
title = "Effects of physical activity and aerobic exercise capacity on aortic stiffness in patients with untreated hypertension",
abstract = "Background and Objectives: High aerobic exercise capacity and sport-related physical activity are reported to be inversely associated with arterial stiffness in healthy young adults. However, it is unknown whether increased physical activity and/or high aerobic exercise capacity attenuate arterial stiffness in patients with untreated hypertension. Subjects and Methods: We studied subjects with never-treated hypertension {n=84 (55 males); mean age ± SD, 49±7 years; age range, 36-65 years}. We excluded subjects with a history of diabetes, angina, myocardial infarction, major arrhythmia, or cerebrovascular diseases and those who were taking any cardiovascular medications, including lipid-lowering agents. Carotid intima-media thickness (IMT) and heart-femoral pulse wave velocity (hfPWV) were measured before exercise testing was performed. Physical activity was estimated using a modified Baecke questionnaire. Aerobic exercise capacity was measured with maximal cardiopulmonary exercise testing (maximum oxygen uptake, Vo2max). Results: Linear regression analysis showed a significant inverse correlation between sport-index and hfPWV (r=-0.404; p<0.001), which multiple linear regression analysis showed to be independent of the individual variables of age, gender, body mass index, mean arterial pressure, total cholesterol, fasting blood glucose, and heart rate (beta=-0.277; p=0.004). However, the work- and leisure-indices and Vo2max were not associated with hfPWV (p> 0.05). Carotid IMT was not associated with physical activity indices or Vo2max. Conclusion: In patients with untreated hypertension, increased sport activity was associated with lower aortic stiffness, but high aerobic exercise capacity was not. These results suggest that regular daily exercise, but not exercise capacity, is an important determinant of aortic stiffness in patients with untreated hypertension.",
keywords = "Aortic stiffness, Exercise, Hypertension",
author = "Na, {Sang Hoon} and Kim, {Yong Seok} and Bae, {Jun Ho} and Nah, {Deuk Young} and Kim, {Young Kwon} and Lee, {Myoung Mook} and Hae-Young Kim and Rhee, {Moo Yong}",
year = "2009",
month = "2",
day = "1",
doi = "10.4070/kcj.2009.39.2.52",
language = "English",
volume = "39",
pages = "52--56",
journal = "Korean Circulation Journal",
issn = "1738-5520",
publisher = "Korean Society of Circulation",
number = "2",

}

TY - JOUR

T1 - Effects of physical activity and aerobic exercise capacity on aortic stiffness in patients with untreated hypertension

AU - Na, Sang Hoon

AU - Kim, Yong Seok

AU - Bae, Jun Ho

AU - Nah, Deuk Young

AU - Kim, Young Kwon

AU - Lee, Myoung Mook

AU - Kim, Hae-Young

AU - Rhee, Moo Yong

PY - 2009/2/1

Y1 - 2009/2/1

N2 - Background and Objectives: High aerobic exercise capacity and sport-related physical activity are reported to be inversely associated with arterial stiffness in healthy young adults. However, it is unknown whether increased physical activity and/or high aerobic exercise capacity attenuate arterial stiffness in patients with untreated hypertension. Subjects and Methods: We studied subjects with never-treated hypertension {n=84 (55 males); mean age ± SD, 49±7 years; age range, 36-65 years}. We excluded subjects with a history of diabetes, angina, myocardial infarction, major arrhythmia, or cerebrovascular diseases and those who were taking any cardiovascular medications, including lipid-lowering agents. Carotid intima-media thickness (IMT) and heart-femoral pulse wave velocity (hfPWV) were measured before exercise testing was performed. Physical activity was estimated using a modified Baecke questionnaire. Aerobic exercise capacity was measured with maximal cardiopulmonary exercise testing (maximum oxygen uptake, Vo2max). Results: Linear regression analysis showed a significant inverse correlation between sport-index and hfPWV (r=-0.404; p<0.001), which multiple linear regression analysis showed to be independent of the individual variables of age, gender, body mass index, mean arterial pressure, total cholesterol, fasting blood glucose, and heart rate (beta=-0.277; p=0.004). However, the work- and leisure-indices and Vo2max were not associated with hfPWV (p> 0.05). Carotid IMT was not associated with physical activity indices or Vo2max. Conclusion: In patients with untreated hypertension, increased sport activity was associated with lower aortic stiffness, but high aerobic exercise capacity was not. These results suggest that regular daily exercise, but not exercise capacity, is an important determinant of aortic stiffness in patients with untreated hypertension.

AB - Background and Objectives: High aerobic exercise capacity and sport-related physical activity are reported to be inversely associated with arterial stiffness in healthy young adults. However, it is unknown whether increased physical activity and/or high aerobic exercise capacity attenuate arterial stiffness in patients with untreated hypertension. Subjects and Methods: We studied subjects with never-treated hypertension {n=84 (55 males); mean age ± SD, 49±7 years; age range, 36-65 years}. We excluded subjects with a history of diabetes, angina, myocardial infarction, major arrhythmia, or cerebrovascular diseases and those who were taking any cardiovascular medications, including lipid-lowering agents. Carotid intima-media thickness (IMT) and heart-femoral pulse wave velocity (hfPWV) were measured before exercise testing was performed. Physical activity was estimated using a modified Baecke questionnaire. Aerobic exercise capacity was measured with maximal cardiopulmonary exercise testing (maximum oxygen uptake, Vo2max). Results: Linear regression analysis showed a significant inverse correlation between sport-index and hfPWV (r=-0.404; p<0.001), which multiple linear regression analysis showed to be independent of the individual variables of age, gender, body mass index, mean arterial pressure, total cholesterol, fasting blood glucose, and heart rate (beta=-0.277; p=0.004). However, the work- and leisure-indices and Vo2max were not associated with hfPWV (p> 0.05). Carotid IMT was not associated with physical activity indices or Vo2max. Conclusion: In patients with untreated hypertension, increased sport activity was associated with lower aortic stiffness, but high aerobic exercise capacity was not. These results suggest that regular daily exercise, but not exercise capacity, is an important determinant of aortic stiffness in patients with untreated hypertension.

KW - Aortic stiffness

KW - Exercise

KW - Hypertension

UR - http://www.scopus.com/inward/record.url?scp=61849087763&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=61849087763&partnerID=8YFLogxK

U2 - 10.4070/kcj.2009.39.2.52

DO - 10.4070/kcj.2009.39.2.52

M3 - Article

AN - SCOPUS:61849087763

VL - 39

SP - 52

EP - 56

JO - Korean Circulation Journal

JF - Korean Circulation Journal

SN - 1738-5520

IS - 2

ER -