Effects of renal replacement therapy in patients receiving extracorporeal membrane oxygenation: A meta-analysis

Seon Sook Han, Hyun Jung Kim, Seung Joon Lee, Woo Jin Kim, Youngi Hong, Hui Young Lee, Seo Young Song, Hae Hyuk Jung, Hyeong Sik Ahn, Il Min Ahn, Hyunjeong Baek

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

The use of renal replacement therapy (RRT) in patients receiving extracorporeal membrane oxygenation (ECMO) is increasing, but the effect of RRT on ECMO is controversial. We performed a meta-analysis to determine whether RRT is related to higher mortality in patients receiving ECMO. We searched MEDLINE, EMBASE, the Cochrane Library, and KoreaMed and found 43 observational studies with 21,624 patients receiving ECMO and then compared inpatient mortality rates of patients receiving ECMO both with and without RRT. The risk ratio (RR) of mortality between patients receiving RRT and those not receiving RRT tended to decrease as the mortality of the group not receiving RRT increased. Among patients with RRT use rates of 30% and higher, the overall mortality rates for all patients receiving ECMO tended to decrease. We found that the increase in the RR for RRT tended to be greater the longer the initiation of RRT was delayed. We suggest that in patients receiving ECMO who have high RRT use rates, RRT may decrease mortality rates.

Original languageEnglish
Pages (from-to)1485-1495
Number of pages11
JournalAnnals of Thoracic Surgery
Volume100
Issue number4
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Extracorporeal Membrane Oxygenation
Renal Replacement Therapy
Meta-Analysis
Mortality
Odds Ratio
MEDLINE
Libraries
Observational Studies
Inpatients

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Effects of renal replacement therapy in patients receiving extracorporeal membrane oxygenation : A meta-analysis. / Han, Seon Sook; Kim, Hyun Jung; Lee, Seung Joon; Kim, Woo Jin; Hong, Youngi; Lee, Hui Young; Song, Seo Young; Jung, Hae Hyuk; Ahn, Hyeong Sik; Ahn, Il Min; Baek, Hyunjeong.

In: Annals of Thoracic Surgery, Vol. 100, No. 4, 01.01.2015, p. 1485-1495.

Research output: Contribution to journalReview article

Han, SS, Kim, HJ, Lee, SJ, Kim, WJ, Hong, Y, Lee, HY, Song, SY, Jung, HH, Ahn, HS, Ahn, IM & Baek, H 2015, 'Effects of renal replacement therapy in patients receiving extracorporeal membrane oxygenation: A meta-analysis', Annals of Thoracic Surgery, vol. 100, no. 4, pp. 1485-1495. https://doi.org/10.1016/j.athoracsur.2015.06.018
Han, Seon Sook ; Kim, Hyun Jung ; Lee, Seung Joon ; Kim, Woo Jin ; Hong, Youngi ; Lee, Hui Young ; Song, Seo Young ; Jung, Hae Hyuk ; Ahn, Hyeong Sik ; Ahn, Il Min ; Baek, Hyunjeong. / Effects of renal replacement therapy in patients receiving extracorporeal membrane oxygenation : A meta-analysis. In: Annals of Thoracic Surgery. 2015 ; Vol. 100, No. 4. pp. 1485-1495.
@article{925053e6c6254eb79c12261341dac847,
title = "Effects of renal replacement therapy in patients receiving extracorporeal membrane oxygenation: A meta-analysis",
abstract = "The use of renal replacement therapy (RRT) in patients receiving extracorporeal membrane oxygenation (ECMO) is increasing, but the effect of RRT on ECMO is controversial. We performed a meta-analysis to determine whether RRT is related to higher mortality in patients receiving ECMO. We searched MEDLINE, EMBASE, the Cochrane Library, and KoreaMed and found 43 observational studies with 21,624 patients receiving ECMO and then compared inpatient mortality rates of patients receiving ECMO both with and without RRT. The risk ratio (RR) of mortality between patients receiving RRT and those not receiving RRT tended to decrease as the mortality of the group not receiving RRT increased. Among patients with RRT use rates of 30{\%} and higher, the overall mortality rates for all patients receiving ECMO tended to decrease. We found that the increase in the RR for RRT tended to be greater the longer the initiation of RRT was delayed. We suggest that in patients receiving ECMO who have high RRT use rates, RRT may decrease mortality rates.",
author = "Han, {Seon Sook} and Kim, {Hyun Jung} and Lee, {Seung Joon} and Kim, {Woo Jin} and Youngi Hong and Lee, {Hui Young} and Song, {Seo Young} and Jung, {Hae Hyuk} and Ahn, {Hyeong Sik} and Ahn, {Il Min} and Hyunjeong Baek",
year = "2015",
month = "1",
day = "1",
doi = "10.1016/j.athoracsur.2015.06.018",
language = "English",
volume = "100",
pages = "1485--1495",
journal = "Annals of Thoracic Surgery",
issn = "0003-4975",
publisher = "Elsevier USA",
number = "4",

}

TY - JOUR

T1 - Effects of renal replacement therapy in patients receiving extracorporeal membrane oxygenation

T2 - A meta-analysis

AU - Han, Seon Sook

AU - Kim, Hyun Jung

AU - Lee, Seung Joon

AU - Kim, Woo Jin

AU - Hong, Youngi

AU - Lee, Hui Young

AU - Song, Seo Young

AU - Jung, Hae Hyuk

AU - Ahn, Hyeong Sik

AU - Ahn, Il Min

AU - Baek, Hyunjeong

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The use of renal replacement therapy (RRT) in patients receiving extracorporeal membrane oxygenation (ECMO) is increasing, but the effect of RRT on ECMO is controversial. We performed a meta-analysis to determine whether RRT is related to higher mortality in patients receiving ECMO. We searched MEDLINE, EMBASE, the Cochrane Library, and KoreaMed and found 43 observational studies with 21,624 patients receiving ECMO and then compared inpatient mortality rates of patients receiving ECMO both with and without RRT. The risk ratio (RR) of mortality between patients receiving RRT and those not receiving RRT tended to decrease as the mortality of the group not receiving RRT increased. Among patients with RRT use rates of 30% and higher, the overall mortality rates for all patients receiving ECMO tended to decrease. We found that the increase in the RR for RRT tended to be greater the longer the initiation of RRT was delayed. We suggest that in patients receiving ECMO who have high RRT use rates, RRT may decrease mortality rates.

AB - The use of renal replacement therapy (RRT) in patients receiving extracorporeal membrane oxygenation (ECMO) is increasing, but the effect of RRT on ECMO is controversial. We performed a meta-analysis to determine whether RRT is related to higher mortality in patients receiving ECMO. We searched MEDLINE, EMBASE, the Cochrane Library, and KoreaMed and found 43 observational studies with 21,624 patients receiving ECMO and then compared inpatient mortality rates of patients receiving ECMO both with and without RRT. The risk ratio (RR) of mortality between patients receiving RRT and those not receiving RRT tended to decrease as the mortality of the group not receiving RRT increased. Among patients with RRT use rates of 30% and higher, the overall mortality rates for all patients receiving ECMO tended to decrease. We found that the increase in the RR for RRT tended to be greater the longer the initiation of RRT was delayed. We suggest that in patients receiving ECMO who have high RRT use rates, RRT may decrease mortality rates.

UR - http://www.scopus.com/inward/record.url?scp=84952716631&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84952716631&partnerID=8YFLogxK

U2 - 10.1016/j.athoracsur.2015.06.018

DO - 10.1016/j.athoracsur.2015.06.018

M3 - Review article

C2 - 26341602

AN - SCOPUS:84952716631

VL - 100

SP - 1485

EP - 1495

JO - Annals of Thoracic Surgery

JF - Annals of Thoracic Surgery

SN - 0003-4975

IS - 4

ER -