Abstract
This paper describes the formation and characterization of liposome entrapping the silver nanoparticles in bilayer. Silver nanoparticles were entrapped in the bilayer of dipalmitoylphosphatidylcholine (DPPC) liposome, named as silver-loaded liposome. Specifically, above the gel to liquid-crystalline phase transition temperature of this lipid (i.e., 41°C), it was observed that membrane fluidities of silver-loaded liposomes were increased, and fluorescence anisotropy values were reduced from 0.114 to 0.097. This might be due to the structural modifications and interactions between DPPC molecules and silver nanoparticles within the bilayer. It was also confirmed that silver nanoparticles were entrapped in hydrophobic region of lipid bilayer with transmission electron microscopy (TEM) and electron energy loss spectroscopy (EELS) measurements.
| Original language | English |
|---|---|
| Pages (from-to) | 117-122 |
| Number of pages | 6 |
| Journal | Colloids and Surfaces B: Biointerfaces |
| Volume | 44 |
| Issue number | 2-3 |
| DOIs | |
| Publication status | Published - 2005 Aug 1 |
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Keywords
- Bilayer
- Liposomes
- Membrane fluidity
- Silver nanoparticle
ASJC Scopus subject areas
- Biotechnology
- Colloid and Surface Chemistry
- Physical and Theoretical Chemistry
- Surfaces and Interfaces
Cite this
Effects of silver nanoparticles on the fluidity of bilayer in phospholipid liposome. / Park, Sung Hee; Oh, Seong Geun; Mun, Ji Young; Han, Sung Sik.
In: Colloids and Surfaces B: Biointerfaces, Vol. 44, No. 2-3, 01.08.2005, p. 117-122.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of silver nanoparticles on the fluidity of bilayer in phospholipid liposome
AU - Park, Sung Hee
AU - Oh, Seong Geun
AU - Mun, Ji Young
AU - Han, Sung Sik
PY - 2005/8/1
Y1 - 2005/8/1
N2 - This paper describes the formation and characterization of liposome entrapping the silver nanoparticles in bilayer. Silver nanoparticles were entrapped in the bilayer of dipalmitoylphosphatidylcholine (DPPC) liposome, named as silver-loaded liposome. Specifically, above the gel to liquid-crystalline phase transition temperature of this lipid (i.e., 41°C), it was observed that membrane fluidities of silver-loaded liposomes were increased, and fluorescence anisotropy values were reduced from 0.114 to 0.097. This might be due to the structural modifications and interactions between DPPC molecules and silver nanoparticles within the bilayer. It was also confirmed that silver nanoparticles were entrapped in hydrophobic region of lipid bilayer with transmission electron microscopy (TEM) and electron energy loss spectroscopy (EELS) measurements.
AB - This paper describes the formation and characterization of liposome entrapping the silver nanoparticles in bilayer. Silver nanoparticles were entrapped in the bilayer of dipalmitoylphosphatidylcholine (DPPC) liposome, named as silver-loaded liposome. Specifically, above the gel to liquid-crystalline phase transition temperature of this lipid (i.e., 41°C), it was observed that membrane fluidities of silver-loaded liposomes were increased, and fluorescence anisotropy values were reduced from 0.114 to 0.097. This might be due to the structural modifications and interactions between DPPC molecules and silver nanoparticles within the bilayer. It was also confirmed that silver nanoparticles were entrapped in hydrophobic region of lipid bilayer with transmission electron microscopy (TEM) and electron energy loss spectroscopy (EELS) measurements.
KW - Bilayer
KW - Liposomes
KW - Membrane fluidity
KW - Silver nanoparticle
UR - http://www.scopus.com/inward/record.url?scp=23444455777&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=23444455777&partnerID=8YFLogxK
U2 - 10.1016/j.colsurfb.2005.06.002
DO - 10.1016/j.colsurfb.2005.06.002
M3 - Article
C2 - 16040237
AN - SCOPUS:23444455777
VL - 44
SP - 117
EP - 122
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
SN - 0927-7765
IS - 2-3
ER -