Effects of the Polysaccharide from the Sporophyll of Brown Alga Undaria Pinnatifida on Serum Lipid Profile and Fat Tissue Accumulation in Rats Fed a High-Fat Diet

Byoung Mok Kim, Jae Ho Park, Dong Soo Kim, Young Myung Kim, Joon Young Jun, In Hak Jeong, Young Min Chi

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Abstract

We investigated the effects of the polysaccharide from the sporophyll of a selected brown alga Undaria pinnatifida on serum lipid profile, fat tissue accumulation, and gastrointestinal transit time in rats fed a high-fat diet. The algal polysaccharide (AP) was prepared by the treatment of multiple cellulase-producing fungi Trichoderma reesei and obtained from the sporophyll with a yield of 38.7% (dry basis). The AP was mostly composed of alginate and fucoidan (up to 89%) in a ratio of 3.75:1. The AP was added to the high-fat diet in concentrations of 0.6% and 1.7% and was given to male Sprague–Dawley rats (5-wk-old) for 5 wk. The 1.7% AP addition notably reduced body weight gain and fat tissue accumulation, and it improved the serum lipid profile, including triglycerides, total cholesterol, and very low-density lipoprotein-cholesterol. The effects were associated with increased feces weight and shortened gastrointestinal transit time. In addition, the lipid peroxidation of the liver was decreased in both groups.

Original languageEnglish
Pages (from-to)H1840-H1845
JournalJournal of Food Science
Volume81
Issue number7
DOIs
Publication statusPublished - 2016 Jul 1

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Keywords

  • algal dietary fiber
  • cellulase-producing fungi
  • high-fat diet
  • marine algae
  • rat

ASJC Scopus subject areas

  • Food Science

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