Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique

Dae Yul Yang, Kyungtae Ko, Seong Ho Lee, Du Geon Moon, Jong Wook Kim, Won Ki Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 min and 6.6 ± 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 ± 3.5 cm2 and 33.6 ± 5.4 cm2, respectively, representing a mean increase of 68.7% ± 14.0% (P < 0.001). Sixteen individuals (88.9%) were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation.

Original languageEnglish
Pages (from-to)80-84
Number of pages5
JournalAsian Journal of Andrology
Volume20
Issue number1
DOIs
Publication statusPublished - 2018 Jan 1

Keywords

  • cosmetic technique
  • dermal fllers
  • dextran
  • glans penis

ASJC Scopus subject areas

  • Urology

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