Abstract
Helicobacter pylori (H. pylori) plays an important role in gastric carcinogenesis, as the majority of gastric cancers develop from H. pylori-infected gastric mucosa. The rate of early gastric cancer diagnosis has increased in Japan and Korea, where H. pylori infection and gastric cancer are highly prevalent. Early intestinal-type gastric cancer without concomitant lymph node metastasis is usually treated by endoscopic resection. Secondary metachronous gastric cancers often develop because atrophic mucosa left untreated after endoscopic treatment confers a high risk of gastric cancer. The efficacy of H. pylori eradication for the prevention of metachronous gastric cancer remains controversial. However, in patients who undergo endoscopic resection of early gastric cancer, H. pylori eradication is recommended to suppress or delay metachronous gastric cancer. Careful and regularly scheduled endoscopy should be performed to detect minute metachronous gastric cancer after endoscopic resection.
| Original language | English |
|---|---|
| Pages (from-to) | 2760-2764 |
| Number of pages | 5 |
| Journal | World Journal of Gastroenterology |
| Volume | 20 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
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Keywords
- Endoscopic resection
- Gastric cancer
- Helicobacter pylori
- Metachronous cancer
ASJC Scopus subject areas
- Gastroenterology
Cite this
Efficacy of Helicobacter pylori eradication for the prevention of metachronous gastric cancer after endoscopic resection for early gastric cancer. / Jang, Jae Young; Chun, Hoon-Jai.
In: World Journal of Gastroenterology, Vol. 20, No. 11, 01.01.2014, p. 2760-2764.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Efficacy of Helicobacter pylori eradication for the prevention of metachronous gastric cancer after endoscopic resection for early gastric cancer
AU - Jang, Jae Young
AU - Chun, Hoon-Jai
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Helicobacter pylori (H. pylori) plays an important role in gastric carcinogenesis, as the majority of gastric cancers develop from H. pylori-infected gastric mucosa. The rate of early gastric cancer diagnosis has increased in Japan and Korea, where H. pylori infection and gastric cancer are highly prevalent. Early intestinal-type gastric cancer without concomitant lymph node metastasis is usually treated by endoscopic resection. Secondary metachronous gastric cancers often develop because atrophic mucosa left untreated after endoscopic treatment confers a high risk of gastric cancer. The efficacy of H. pylori eradication for the prevention of metachronous gastric cancer remains controversial. However, in patients who undergo endoscopic resection of early gastric cancer, H. pylori eradication is recommended to suppress or delay metachronous gastric cancer. Careful and regularly scheduled endoscopy should be performed to detect minute metachronous gastric cancer after endoscopic resection.
AB - Helicobacter pylori (H. pylori) plays an important role in gastric carcinogenesis, as the majority of gastric cancers develop from H. pylori-infected gastric mucosa. The rate of early gastric cancer diagnosis has increased in Japan and Korea, where H. pylori infection and gastric cancer are highly prevalent. Early intestinal-type gastric cancer without concomitant lymph node metastasis is usually treated by endoscopic resection. Secondary metachronous gastric cancers often develop because atrophic mucosa left untreated after endoscopic treatment confers a high risk of gastric cancer. The efficacy of H. pylori eradication for the prevention of metachronous gastric cancer remains controversial. However, in patients who undergo endoscopic resection of early gastric cancer, H. pylori eradication is recommended to suppress or delay metachronous gastric cancer. Careful and regularly scheduled endoscopy should be performed to detect minute metachronous gastric cancer after endoscopic resection.
KW - Endoscopic resection
KW - Gastric cancer
KW - Helicobacter pylori
KW - Metachronous cancer
UR - http://www.scopus.com/inward/record.url?scp=84896446781&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84896446781&partnerID=8YFLogxK
U2 - 10.3748/wjg.v20.i11.2760
DO - 10.3748/wjg.v20.i11.2760
M3 - Article
VL - 20
SP - 2760
EP - 2764
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 11
ER -