Efficacy of single-session percutaneous drainage and 50% acetic acid sclerotherapy for treatment of simple renal cysts

Se Hwan Kwon, Joo Hyeong Oh, Tae-Seok Seo, Ho Chul Park

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: To evaluate the efficacy and long-term results of single-session 50% acetic acid sclerotherapy for the treatment of simple renal cysts, and to compare the therapeutic results of 5 and 20 min sclerosant dwell techniques. Methods: During the past 9 years, 50% acetic acid sclerotherapy was performed on 67 cysts in 66 patients. An acetic acid volume corresponding to a mean of 23% of the aspirated cyst volume was injected into the cysts. A 20 min dwell time with position changes was performed in 32 cysts (31 patients; group I) and 8% of volume for a 5 min dwell time in 35 cysts (35 patients; group II). Three- and 6-month sonographic or CT follow-up was performed for a minimum of 1 year. Complete regression was defined as no remaining cyst measurable on sonography with or without a scar at the renal cortex. Partial regression was defined as a decreased cyst volume compared with that before sclerotherapy. The Mann-Whitney U-test was used to compare the therapeutic results between the two groups. Results: For 67 simple renal cysts, complete regression on follow-up was observed in 21 of 32 cysts (66%; group I) and 22 of 35 cysts (63%; group II); the remaining 24 cysts all showed partial regression. The partial reduction rate of the cyst's volume was 97.4% (91.3-99.4%) in group I and 96.9% (90.8-99.5 %) in group II. There were no procedure-related major complications, and no statistically significant differences in the complete regression and partial volume reduction rates between the two groups (p > 0.05). Conclusion: Fifty percent acetic acid is an effective and safe sclerosing agent for simple renal cysts. Fifty percent acetic acid sclerotherapy with a 5 min sclerosant dwell time, using a volume of about 10% of the aspirated volume, is sufficient for satisfactory results of simple renal cyst sclerotherapy.

Original languageEnglish
Pages (from-to)1227-1233
Number of pages7
JournalCardioVascular and Interventional Radiology
Volume30
Issue number6
DOIs
Publication statusPublished - 2007 Nov 1

Fingerprint

Sclerotherapy
Acetic Acid
Cysts
Drainage
Kidney
Sclerosing Solutions
Therapeutics
Nonparametric Statistics

Keywords

  • Cyst
  • Interventional radiology
  • Kidney cysts
  • Percutaneous drainage
  • Sclerotherapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Efficacy of single-session percutaneous drainage and 50% acetic acid sclerotherapy for treatment of simple renal cysts. / Kwon, Se Hwan; Oh, Joo Hyeong; Seo, Tae-Seok; Park, Ho Chul.

In: CardioVascular and Interventional Radiology, Vol. 30, No. 6, 01.11.2007, p. 1227-1233.

Research output: Contribution to journalArticle

@article{6a436a907ffd4dc7845786269ff1f542,
title = "Efficacy of single-session percutaneous drainage and 50{\%} acetic acid sclerotherapy for treatment of simple renal cysts",
abstract = "Purpose: To evaluate the efficacy and long-term results of single-session 50{\%} acetic acid sclerotherapy for the treatment of simple renal cysts, and to compare the therapeutic results of 5 and 20 min sclerosant dwell techniques. Methods: During the past 9 years, 50{\%} acetic acid sclerotherapy was performed on 67 cysts in 66 patients. An acetic acid volume corresponding to a mean of 23{\%} of the aspirated cyst volume was injected into the cysts. A 20 min dwell time with position changes was performed in 32 cysts (31 patients; group I) and 8{\%} of volume for a 5 min dwell time in 35 cysts (35 patients; group II). Three- and 6-month sonographic or CT follow-up was performed for a minimum of 1 year. Complete regression was defined as no remaining cyst measurable on sonography with or without a scar at the renal cortex. Partial regression was defined as a decreased cyst volume compared with that before sclerotherapy. The Mann-Whitney U-test was used to compare the therapeutic results between the two groups. Results: For 67 simple renal cysts, complete regression on follow-up was observed in 21 of 32 cysts (66{\%}; group I) and 22 of 35 cysts (63{\%}; group II); the remaining 24 cysts all showed partial regression. The partial reduction rate of the cyst's volume was 97.4{\%} (91.3-99.4{\%}) in group I and 96.9{\%} (90.8-99.5 {\%}) in group II. There were no procedure-related major complications, and no statistically significant differences in the complete regression and partial volume reduction rates between the two groups (p > 0.05). Conclusion: Fifty percent acetic acid is an effective and safe sclerosing agent for simple renal cysts. Fifty percent acetic acid sclerotherapy with a 5 min sclerosant dwell time, using a volume of about 10{\%} of the aspirated volume, is sufficient for satisfactory results of simple renal cyst sclerotherapy.",
keywords = "Cyst, Interventional radiology, Kidney cysts, Percutaneous drainage, Sclerotherapy",
author = "Kwon, {Se Hwan} and Oh, {Joo Hyeong} and Tae-Seok Seo and Park, {Ho Chul}",
year = "2007",
month = "11",
day = "1",
doi = "10.1007/s00270-007-9176-5",
language = "English",
volume = "30",
pages = "1227--1233",
journal = "CardioVascular and Interventional Radiology",
issn = "7415-5101",
publisher = "Springer Verlag",
number = "6",

}

TY - JOUR

T1 - Efficacy of single-session percutaneous drainage and 50% acetic acid sclerotherapy for treatment of simple renal cysts

AU - Kwon, Se Hwan

AU - Oh, Joo Hyeong

AU - Seo, Tae-Seok

AU - Park, Ho Chul

PY - 2007/11/1

Y1 - 2007/11/1

N2 - Purpose: To evaluate the efficacy and long-term results of single-session 50% acetic acid sclerotherapy for the treatment of simple renal cysts, and to compare the therapeutic results of 5 and 20 min sclerosant dwell techniques. Methods: During the past 9 years, 50% acetic acid sclerotherapy was performed on 67 cysts in 66 patients. An acetic acid volume corresponding to a mean of 23% of the aspirated cyst volume was injected into the cysts. A 20 min dwell time with position changes was performed in 32 cysts (31 patients; group I) and 8% of volume for a 5 min dwell time in 35 cysts (35 patients; group II). Three- and 6-month sonographic or CT follow-up was performed for a minimum of 1 year. Complete regression was defined as no remaining cyst measurable on sonography with or without a scar at the renal cortex. Partial regression was defined as a decreased cyst volume compared with that before sclerotherapy. The Mann-Whitney U-test was used to compare the therapeutic results between the two groups. Results: For 67 simple renal cysts, complete regression on follow-up was observed in 21 of 32 cysts (66%; group I) and 22 of 35 cysts (63%; group II); the remaining 24 cysts all showed partial regression. The partial reduction rate of the cyst's volume was 97.4% (91.3-99.4%) in group I and 96.9% (90.8-99.5 %) in group II. There were no procedure-related major complications, and no statistically significant differences in the complete regression and partial volume reduction rates between the two groups (p > 0.05). Conclusion: Fifty percent acetic acid is an effective and safe sclerosing agent for simple renal cysts. Fifty percent acetic acid sclerotherapy with a 5 min sclerosant dwell time, using a volume of about 10% of the aspirated volume, is sufficient for satisfactory results of simple renal cyst sclerotherapy.

AB - Purpose: To evaluate the efficacy and long-term results of single-session 50% acetic acid sclerotherapy for the treatment of simple renal cysts, and to compare the therapeutic results of 5 and 20 min sclerosant dwell techniques. Methods: During the past 9 years, 50% acetic acid sclerotherapy was performed on 67 cysts in 66 patients. An acetic acid volume corresponding to a mean of 23% of the aspirated cyst volume was injected into the cysts. A 20 min dwell time with position changes was performed in 32 cysts (31 patients; group I) and 8% of volume for a 5 min dwell time in 35 cysts (35 patients; group II). Three- and 6-month sonographic or CT follow-up was performed for a minimum of 1 year. Complete regression was defined as no remaining cyst measurable on sonography with or without a scar at the renal cortex. Partial regression was defined as a decreased cyst volume compared with that before sclerotherapy. The Mann-Whitney U-test was used to compare the therapeutic results between the two groups. Results: For 67 simple renal cysts, complete regression on follow-up was observed in 21 of 32 cysts (66%; group I) and 22 of 35 cysts (63%; group II); the remaining 24 cysts all showed partial regression. The partial reduction rate of the cyst's volume was 97.4% (91.3-99.4%) in group I and 96.9% (90.8-99.5 %) in group II. There were no procedure-related major complications, and no statistically significant differences in the complete regression and partial volume reduction rates between the two groups (p > 0.05). Conclusion: Fifty percent acetic acid is an effective and safe sclerosing agent for simple renal cysts. Fifty percent acetic acid sclerotherapy with a 5 min sclerosant dwell time, using a volume of about 10% of the aspirated volume, is sufficient for satisfactory results of simple renal cyst sclerotherapy.

KW - Cyst

KW - Interventional radiology

KW - Kidney cysts

KW - Percutaneous drainage

KW - Sclerotherapy

UR - http://www.scopus.com/inward/record.url?scp=35848938962&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35848938962&partnerID=8YFLogxK

U2 - 10.1007/s00270-007-9176-5

DO - 10.1007/s00270-007-9176-5

M3 - Article

VL - 30

SP - 1227

EP - 1233

JO - CardioVascular and Interventional Radiology

JF - CardioVascular and Interventional Radiology

SN - 7415-5101

IS - 6

ER -