In this paper, we investigate efficient data access algorithms in intelligent transportation system (ITS)-based networks with multi-hop wireless links. We introduce a proxy cache (PC) and propose PC-based poll-each-read (P-PER) and PCbased callback (P-CB) data access algorithms to reduce the transmission cost over the bottleneck wireless links. Extensive simulation results are given to demonstrate the performance of P-PER and P-CB. It is shown that P-PER and P-CB can improve the cache hit performance and reduce the transmission cost significantly. A tradeoff between P-PER and P-CB suggests the need to use a hybrid proxy-based approach to attain optimal performance of data access in ITS-based networks with multi-hop wireless links.