Eight weeks of conjugated linoleic acid supplementation has no effect on antioxidant status in healthy overweight/obese Korean individuals

Jungmi Kim, Hyun Dong Paik, Min Jeong Shin, Eunju Park

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Purpose: The aim of this study was to evaluate the effect of CLA supplementation on antioxidant metabolism in healthy overweight/obese Korean individuals. Methods: We performed a randomized, double-blind, placebo-controlled trial, where 29 healthy overweight/obese (BMI ≥ 23 kg/m 2) participants(2men and27women) were randomly selected to receive placebo (n = 15, 2.4 g olive oil/day) or 2.4 g/day CLA mixture (n = 14, 36.9% of cis-9, trans-11 and 37.9% of trans-10, cis-12) for 8 weeks. Results: There were no significant differences in plasma total radical-trapping antioxidant potential (TRAP), lipid peroxidation (conjugated dienes), lipid-soluble antioxidant vitamin concentration, erythrocyte antioxidant enzyme (superoxide dismutase, catalase, glutathione peroxidase) activities, and leukocyte DNA damage between the CLA and placebo groups. Conclusions: The data suggest that short-term supplementation (8 weeks) with CLA (2.4 g/day) might have no significant effects on lipid peroxidation and antioxidant metabolism.

Original languageEnglish
Pages (from-to)135-141
Number of pages7
JournalEuropean Journal of Nutrition
Volume51
Issue number2
DOIs
Publication statusPublished - 2012 Mar

Keywords

  • Antioxidant status
  • Conjugated linoleic acid
  • Overweight/obese

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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