Abstract
Ethylene was the first plant hormone for which a receptor-dependent signalling pathway was established. The signal transduction pathway is framed around genetically identified factors encompassing membrane receptors through to intra-cellular regulators and then nuclear transcription factors. Recently, the cellular and biochemical connections among these genetic factors have been characterized to reveal a complex and intertwined signalling scheme. For ethylene signalling, the short-lived ETHYLENE INSENSITIVE2 (EIN2) and ETHYLENE INSENSITIVE3 (EIN3) proteins play central roles, and so regulation of the turnover of these proteins by specific E3 ligases serves as a key regulatory step in the pathway. Two antagonistic mitogen-activated protein kinase (MAPK) cascades that modify EIN3 appear to mediate intra-cellular signalling frommembrane receptors to nuclear transcription factors. The identification of further genomic and genetic components and elucidation of their cellular and biochemical roles in EIN2 and EIN3 regulation are thus required to complete the whole ethylene signal transduction pathway. Such a comprehensive understanding of ethylene signal transduction will provide useful information for the selection of genes that can enhance plant adaptations to unfavourable environmental conditions and so secure food production and plant-based renewable bio-energy for human society.
| Original language | English |
|---|---|
| Title of host publication | The Plant Hormone Ethylene |
| Publisher | Wiley-Blackwell |
| Pages | 169-187 |
| Number of pages | 19 |
| Volume | 44 |
| ISBN (Print) | 9781118223086, 9781444330038 |
| DOIs | |
| Publication status | Published - 2012 Feb 14 |
| Externally published | Yes |
Fingerprint
Keywords
- ETHYLENE INSENSITIVE2 (EIN2)
- ETHYLENE INSENSITIVE3 (EIN3)
- Ethylene response factors (ERFs)
- Ethylene signalling
- Mitogen-activated protein kinase (MAPK) cascades
- Protein stability
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
Cite this
EIN2 and EIN3 in Ethylene Signalling. / Cho, Young Hee; Lee, Sangho; Yoo, Sang-Dong.
The Plant Hormone Ethylene. Vol. 44 Wiley-Blackwell, 2012. p. 169-187.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - EIN2 and EIN3 in Ethylene Signalling
AU - Cho, Young Hee
AU - Lee, Sangho
AU - Yoo, Sang-Dong
PY - 2012/2/14
Y1 - 2012/2/14
N2 - Ethylene was the first plant hormone for which a receptor-dependent signalling pathway was established. The signal transduction pathway is framed around genetically identified factors encompassing membrane receptors through to intra-cellular regulators and then nuclear transcription factors. Recently, the cellular and biochemical connections among these genetic factors have been characterized to reveal a complex and intertwined signalling scheme. For ethylene signalling, the short-lived ETHYLENE INSENSITIVE2 (EIN2) and ETHYLENE INSENSITIVE3 (EIN3) proteins play central roles, and so regulation of the turnover of these proteins by specific E3 ligases serves as a key regulatory step in the pathway. Two antagonistic mitogen-activated protein kinase (MAPK) cascades that modify EIN3 appear to mediate intra-cellular signalling frommembrane receptors to nuclear transcription factors. The identification of further genomic and genetic components and elucidation of their cellular and biochemical roles in EIN2 and EIN3 regulation are thus required to complete the whole ethylene signal transduction pathway. Such a comprehensive understanding of ethylene signal transduction will provide useful information for the selection of genes that can enhance plant adaptations to unfavourable environmental conditions and so secure food production and plant-based renewable bio-energy for human society.
AB - Ethylene was the first plant hormone for which a receptor-dependent signalling pathway was established. The signal transduction pathway is framed around genetically identified factors encompassing membrane receptors through to intra-cellular regulators and then nuclear transcription factors. Recently, the cellular and biochemical connections among these genetic factors have been characterized to reveal a complex and intertwined signalling scheme. For ethylene signalling, the short-lived ETHYLENE INSENSITIVE2 (EIN2) and ETHYLENE INSENSITIVE3 (EIN3) proteins play central roles, and so regulation of the turnover of these proteins by specific E3 ligases serves as a key regulatory step in the pathway. Two antagonistic mitogen-activated protein kinase (MAPK) cascades that modify EIN3 appear to mediate intra-cellular signalling frommembrane receptors to nuclear transcription factors. The identification of further genomic and genetic components and elucidation of their cellular and biochemical roles in EIN2 and EIN3 regulation are thus required to complete the whole ethylene signal transduction pathway. Such a comprehensive understanding of ethylene signal transduction will provide useful information for the selection of genes that can enhance plant adaptations to unfavourable environmental conditions and so secure food production and plant-based renewable bio-energy for human society.
KW - ETHYLENE INSENSITIVE2 (EIN2)
KW - ETHYLENE INSENSITIVE3 (EIN3)
KW - Ethylene response factors (ERFs)
KW - Ethylene signalling
KW - Mitogen-activated protein kinase (MAPK) cascades
KW - Protein stability
UR - http://www.scopus.com/inward/record.url?scp=84924404631&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84924404631&partnerID=8YFLogxK
U2 - 10.1002/9781118223086.ch7
DO - 10.1002/9781118223086.ch7
M3 - Chapter
AN - SCOPUS:84924404631
SN - 9781118223086
SN - 9781444330038
VL - 44
SP - 169
EP - 187
BT - The Plant Hormone Ethylene
PB - Wiley-Blackwell
ER -