Electrical characteristics of various submucosal injection fluids for endoscopic mucosal resection

Sanghoon Park, Hoon-Jai Chun, Chul Yong Kim, Ju Young Kim, Jin Su Jang, Yong Dae Kwon, Doo Rang Kim, Bora Keum, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hong Sik Lee, Soon-Ho Um, Sang Woo Lee, Jae Hyun Choi, Chang Duck Kim, Ho Sang Ryu, Jong Hyeon Chang, James Jungho Pak

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Submucosal fluid injection, prerequisite to endoscopic mucosal resection, necessitates detailed evaluation for proper selection. We aimed to compare height of gastric tissues after submucosal injection, and to verify electrical implications of injectants. Porcine stomach pieces were cut out, and eight solutions were used: normal saline, 0.5% sodium hyaluronate (SH), 0.25% SH, hydroxypropyl methylcellulose, 10% glycerin, fibrinogen, 1% sodium alginate (SA), and 2.5% SA. Elevated heights were measured after submucosal injection of the eight fluids, and electrical impedance was measured for fluids plus a reference solution (0.01 N KCl) with a potentiostat electro-impedance spectrometry and an insulation-tipped knife. Resistivity was calculated thereafter. Normal saline and 10% glycerin solution showed greater height diminution. Resistivity were in the range of 80-110 Ω cm, except for 309.7 Ω cm for fibrinogen. Higher resistivity may improve performance of electrosurgery, probably by strengthening impedance and heat dissipation. Further studies are required to back up this basic experiment for clinical application.

Original languageEnglish
Pages (from-to)1678-1682
Number of pages5
JournalDigestive Diseases and Sciences
Volume53
Issue number6
DOIs
Publication statusPublished - 2008 Jun 1

Fingerprint

Electric Impedance
Hyaluronic Acid
Glycerol
Fibrinogen
Injections
Stomach
Electrosurgery
Spectrum Analysis
Swine
Hot Temperature
Endoscopic Mucosal Resection
alginic acid

Keywords

  • Electric impedance
  • Gastric cancer
  • Gastroscopes
  • Intralesional injections

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Electrical characteristics of various submucosal injection fluids for endoscopic mucosal resection. / Park, Sanghoon; Chun, Hoon-Jai; Kim, Chul Yong; Kim, Ju Young; Jang, Jin Su; Kwon, Yong Dae; Kim, Doo Rang; Keum, Bora; Seo, Yeon Seok; Kim, Yong Sik; Jeen, Yoon Tae; Lee, Hong Sik; Um, Soon-Ho; Lee, Sang Woo; Choi, Jae Hyun; Kim, Chang Duck; Ryu, Ho Sang; Chang, Jong Hyeon; Pak, James Jungho.

In: Digestive Diseases and Sciences, Vol. 53, No. 6, 01.06.2008, p. 1678-1682.

Research output: Contribution to journalArticle

Park, Sanghoon ; Chun, Hoon-Jai ; Kim, Chul Yong ; Kim, Ju Young ; Jang, Jin Su ; Kwon, Yong Dae ; Kim, Doo Rang ; Keum, Bora ; Seo, Yeon Seok ; Kim, Yong Sik ; Jeen, Yoon Tae ; Lee, Hong Sik ; Um, Soon-Ho ; Lee, Sang Woo ; Choi, Jae Hyun ; Kim, Chang Duck ; Ryu, Ho Sang ; Chang, Jong Hyeon ; Pak, James Jungho. / Electrical characteristics of various submucosal injection fluids for endoscopic mucosal resection. In: Digestive Diseases and Sciences. 2008 ; Vol. 53, No. 6. pp. 1678-1682.
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