Electrochemical detection of DNA mutations on a PNA-modified electrode utilizing a single-stranded DNA specific endonuclease

Sujeong Shin, Byoung Yeon Won, Cheulhee Jung, Sung Chul Shin, Dae Yeon Cho, Soo Suk Lee, Hyun Gyu Park

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Utilizing a peptide nucleic acid (PNA)-modified electrode and a single-stranded DNA specific endonuclease, a novel electrochemical method to identify DNA mutations has been developed and represents a totally new strategy for the electrochemical diagnosis of human genetic mutations.

Original languageEnglish
Pages (from-to)6611-6613
Number of pages3
JournalChemical Communications
Volume47
Issue number23
DOIs
Publication statusPublished - 2011 Jun 21
Externally publishedYes

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ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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