Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique

Sung Up Hwang; Ji Min Choi; Hyun Ho Yang; Chang Hoon Kim; Chulhee Jung; Hyun Gyu Park; Yang Kyu Choi; Jun Bo Yoon

doi:10.1109/MEMSYS.2011.5734560

Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique

Sung Up Hwang, Ji Min Choi, Hyun Ho Yang, Chang Hoon Kim, Chulhee Jung, Hyun Gyu Park, Yang Kyu Choi, Jun Bo Yoon

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

This paper reports a novel electrical detection of label-free DNA by use of a MEMS electrostatic micro-switch. The electrostatic micro-switch detects the immobilization of probe oligonucleotides and their hybridization with target oligonucleotides using pull-in voltage shift in the micro-switch originated from negative charges of the oligonucleotides. A numerical simulation is analyzed to support this concept. The proposed biomolecule detection method using an electrostatic micro-switch represents a protocol for a new candidate of microactuator-type sensor.

Original language	English
Title of host publication	2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011
Pages	857-860
Number of pages	4
DOIs	https://doi.org/10.1109/MEMSYS.2011.5734560
Publication status	Published - 2011
Externally published	Yes
Event	24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011 - Cancun, Mexico Duration: 2011 Jan 23 → 2011 Jan 27

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Other

Other	24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011
Country/Territory	Mexico
City	Cancun
Period	11/1/23 → 11/1/27

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

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10.1109/MEMSYS.2011.5734560

Cite this

Hwang, S. U., Choi, J. M., Yang, H. H., Kim, C. H., Jung, C., Park, H. G., Choi, Y. K., & Yoon, J. B. (2011). Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique. In 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011 (pp. 857-860). [5734560] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2011.5734560

Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique. / Hwang, Sung Up; Choi, Ji Min; Yang, Hyun Ho et al.

2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011. 2011. p. 857-860 5734560 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hwang, SU, Choi, JM, Yang, HH, Kim, CH, Jung, C, Park, HG, Choi, YK & Yoon, JB 2011, Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique. in 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011., 5734560, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 857-860, 24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011, Cancun, Mexico, 11/1/23. https://doi.org/10.1109/MEMSYS.2011.5734560

Hwang SU, Choi JM, Yang HH, Kim CH, Jung C, Park HG et al. Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique. In 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011. 2011. p. 857-860. 5734560. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2011.5734560

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title = "Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique",

abstract = "This paper reports a novel electrical detection of label-free DNA by use of a MEMS electrostatic micro-switch. The electrostatic micro-switch detects the immobilization of probe oligonucleotides and their hybridization with target oligonucleotides using pull-in voltage shift in the micro-switch originated from negative charges of the oligonucleotides. A numerical simulation is analyzed to support this concept. The proposed biomolecule detection method using an electrostatic micro-switch represents a protocol for a new candidate of microactuator-type sensor.",

author = "Hwang, {Sung Up} and Choi, {Ji Min} and Yang, {Hyun Ho} and Kim, {Chang Hoon} and Chulhee Jung and Park, {Hyun Gyu} and Choi, {Yang Kyu} and Yoon, {Jun Bo}",

note = "Copyright: Copyright 2011 Elsevier B.V., All rights reserved.; 24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011 ; Conference date: 23-01-2011 Through 27-01-2011",

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doi = "10.1109/MEMSYS.2011.5734560",

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AU - Yoon, Jun Bo

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AB - This paper reports a novel electrical detection of label-free DNA by use of a MEMS electrostatic micro-switch. The electrostatic micro-switch detects the immobilization of probe oligonucleotides and their hybridization with target oligonucleotides using pull-in voltage shift in the micro-switch originated from negative charges of the oligonucleotides. A numerical simulation is analyzed to support this concept. The proposed biomolecule detection method using an electrostatic micro-switch represents a protocol for a new candidate of microactuator-type sensor.

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Electrostatic switching biosensor - A novel label-free DNA detection using an electrode charging technique

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