Abstract
(Chemical Equation Presented) Elimination reactions of (E)-2,4-(NO 2)2C6H3CH=NOC(O)-C6H 4X (1) promoted by R2NH/R2NH2 + in 70 mol % MeCN(aq) have been studied kinetically. The reactions are second-order and exhibit Brönsted β = 0.27-0.32 and |βlg| = 0.28-0.32. The result can be described by a negligible Pxy interaction coefficient, pxy = ∂β/ ∂pKlg = ∂βlg/∂pKBH ≈ 0, which describes the interaction between the base catalyst and the leaving group. The negligible pxy coefficients are consistent with the (E1cb) irr mechanism.
Original language | English |
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Pages (from-to) | 9451-9453 |
Number of pages | 3 |
Journal | Journal of Organic Chemistry |
Volume | 73 |
Issue number | 23 |
DOIs | |
Publication status | Published - 2008 Dec 5 |
ASJC Scopus subject areas
- Organic Chemistry