Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications

Wei Tao, Na Kong, Xiaoyuan Ji, Yupeng Zhang, Amit Sharma, Jiang Ouyang, Baowen Qi, Junqing Wang, Ni Xie, Chulhun Kang, Han Zhang, Omid C. Farokhzad, Jong Seung Kim

Research output: Contribution to journalReview articlepeer-review

383 Citations (Scopus)


The emergence of novel two-dimensional (2D) monoelemental materials (Xenes) has shown remarkable potential for their applications in different fields of technology, as well as addressing new discoveries in fundamental science. Xenes (e.g., borophene, silicene, germanene, stanene, phosphorene, arsenene, antimonene, bismuthene, and tellurene) are of particular interest because they are the most chemically tractable materials for synthetic exploration. Owing to their excellent physical, chemical, electronic and optical properties, Xenes have been regarded as promising agents for biosensors, bioimaging, therapeutic delivery, and theranostics, as well as in several other new bio-applications. In this tutorial review, we summarize their general properties including the classification of Xenes according to their bulk properties. The synthetic and modification methods of Xenes are also presented. Furthermore, the representative Xene nanoplatforms for various biomedical applications are highlighted. Finally, research progress, challenges, and perspectives for the future development of Xenes in biomedicines are discussed.

Original languageEnglish
Pages (from-to)2891-2912
Number of pages22
JournalChemical Society Reviews
Issue number11
Publication statusPublished - 2019 Jun 7

ASJC Scopus subject areas

  • Chemistry(all)


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