Enantioselective additions of diethylzinc and diphenylzinc to aldehydes using 2-dialkyl-aminomethyl-2′-hydroxy-1,1′-binaphthyls

Dong Hyun Ko, Kyoung Hoon Kim, Deok Chan Ha

Research output: Contribution to journalArticle

114 Citations (Scopus)

Abstract

(graph presented) A set of 2-dialkylaminomethyl-2′-hydroxy-1,1′-binaphthyls was prepared and used in the catalytic asymmetric additions of diethylzinc and diphenylzinc to various types of aldehydes. These binaphthyl-based axially chiral amino alcohols show high enantioselectivity in the addition of organozincs to aromatic and aliphatic aldehydes.

Original languageEnglish
Pages (from-to)3759-3762
Number of pages4
JournalOrganic Letters
Volume4
Issue number21
DOIs
Publication statusPublished - 2002 Oct 17

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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