(graph presented) A set of 2-dialkylaminomethyl-2′-hydroxy-1,1′-binaphthyls was prepared and used in the catalytic asymmetric additions of diethylzinc and diphenylzinc to various types of aldehydes. These binaphthyl-based axially chiral amino alcohols show high enantioselectivity in the addition of organozincs to aromatic and aliphatic aldehydes.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry