Enantioselective additions of diethylzinc and diphenylzinc to aldehydes using 2-dialkyl-aminomethyl-2′-hydroxy-1,1′-binaphthyls

Dong Hyun Ko, Kyoung Hoon Kim, Deok-Chan Ha

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

(graph presented) A set of 2-dialkylaminomethyl-2′-hydroxy-1,1′-binaphthyls was prepared and used in the catalytic asymmetric additions of diethylzinc and diphenylzinc to various types of aldehydes. These binaphthyl-based axially chiral amino alcohols show high enantioselectivity in the addition of organozincs to aromatic and aliphatic aldehydes.

Original languageEnglish
Pages (from-to)3759-3762
Number of pages4
JournalOrganic Letters
Volume4
Issue number21
DOIs
Publication statusPublished - 2002 Oct 17

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aldehydes
Aldehydes
Amino Alcohols
Enantioselectivity
alcohols
diphenylzinc
diethylzinc

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Enantioselective additions of diethylzinc and diphenylzinc to aldehydes using 2-dialkyl-aminomethyl-2′-hydroxy-1,1′-binaphthyls. / Ko, Dong Hyun; Kim, Kyoung Hoon; Ha, Deok-Chan.

In: Organic Letters, Vol. 4, No. 21, 17.10.2002, p. 3759-3762.

Research output: Contribution to journalArticle

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