Abstract
Low-grade endometrial stromal sarcoma (ESS) is an uncommon gynecologic malignancy of mesodermal origin. Pulmonary metastasis of low-grade ESS can occur years and decades after the treatment of the primary disease. Low-grade ESS is frequently mistaken as benign uterine neoplasm like uterine leiomyoma, which can potentially lead to a misdiagnosis. We present a case of a 42-year-old woman with low-grade ESS, that initially presented as an incidental lung mass with multiple pulmonary nodules, seven years after an uterine myomectomy. A 6.9x5.8 cm-sized intrapelvic mass suspected of uterine origin was discovered while searching for potential extrathoracic primary origin. A pelviscopy and simultaneous thoracoscopic lung biopsy were conducted for pathologic diagnosis. Finally, the diagnosis was confirmed as low-grade ESS with lung metastasis based on the histopathologic examination with immunohistochemical stain, which was showed positive for CD 10 and hormone receptor markers (estrogen and progesterone receptors) in both pelvic and lung specimens.
| Original language | English |
|---|---|
| Pages (from-to) | 131-135 |
| Number of pages | 5 |
| Journal | Tuberculosis and Respiratory Diseases |
| Volume | 76 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
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Keywords
- Multiple pulmonary nodules
- Neoplasm metastasis
- Sarcoma, endometrial stromal
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Infectious Diseases
Cite this
Endometrial stromal sarcoma presented as an incidental lung mass with multiple pulmonary nodules. / Kang, Dong Oh; Choi, Sue In; Oh, Jee Youn; Sim, Jae Kyeom; Choi, Jong Hyun; Choo, Ji Yung; Hwang, Jin Wook; Lee, Seung Heon; Lee, Ju-Han; Lee, Ki Yeol; Shin, Chol; Kim, Je Hyeong.
In: Tuberculosis and Respiratory Diseases, Vol. 76, No. 3, 01.01.2014, p. 131-135.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Endometrial stromal sarcoma presented as an incidental lung mass with multiple pulmonary nodules
AU - Kang, Dong Oh
AU - Choi, Sue In
AU - Oh, Jee Youn
AU - Sim, Jae Kyeom
AU - Choi, Jong Hyun
AU - Choo, Ji Yung
AU - Hwang, Jin Wook
AU - Lee, Seung Heon
AU - Lee, Ju-Han
AU - Lee, Ki Yeol
AU - Shin, Chol
AU - Kim, Je Hyeong
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Low-grade endometrial stromal sarcoma (ESS) is an uncommon gynecologic malignancy of mesodermal origin. Pulmonary metastasis of low-grade ESS can occur years and decades after the treatment of the primary disease. Low-grade ESS is frequently mistaken as benign uterine neoplasm like uterine leiomyoma, which can potentially lead to a misdiagnosis. We present a case of a 42-year-old woman with low-grade ESS, that initially presented as an incidental lung mass with multiple pulmonary nodules, seven years after an uterine myomectomy. A 6.9x5.8 cm-sized intrapelvic mass suspected of uterine origin was discovered while searching for potential extrathoracic primary origin. A pelviscopy and simultaneous thoracoscopic lung biopsy were conducted for pathologic diagnosis. Finally, the diagnosis was confirmed as low-grade ESS with lung metastasis based on the histopathologic examination with immunohistochemical stain, which was showed positive for CD 10 and hormone receptor markers (estrogen and progesterone receptors) in both pelvic and lung specimens.
AB - Low-grade endometrial stromal sarcoma (ESS) is an uncommon gynecologic malignancy of mesodermal origin. Pulmonary metastasis of low-grade ESS can occur years and decades after the treatment of the primary disease. Low-grade ESS is frequently mistaken as benign uterine neoplasm like uterine leiomyoma, which can potentially lead to a misdiagnosis. We present a case of a 42-year-old woman with low-grade ESS, that initially presented as an incidental lung mass with multiple pulmonary nodules, seven years after an uterine myomectomy. A 6.9x5.8 cm-sized intrapelvic mass suspected of uterine origin was discovered while searching for potential extrathoracic primary origin. A pelviscopy and simultaneous thoracoscopic lung biopsy were conducted for pathologic diagnosis. Finally, the diagnosis was confirmed as low-grade ESS with lung metastasis based on the histopathologic examination with immunohistochemical stain, which was showed positive for CD 10 and hormone receptor markers (estrogen and progesterone receptors) in both pelvic and lung specimens.
KW - Multiple pulmonary nodules
KW - Neoplasm metastasis
KW - Sarcoma, endometrial stromal
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UR - http://www.scopus.com/inward/citedby.url?scp=84899081893&partnerID=8YFLogxK
U2 - 10.4046/trd.2014.76.3.131
DO - 10.4046/trd.2014.76.3.131
M3 - Article
VL - 76
SP - 131
EP - 135
JO - Tuberculosis and Respiratory Diseases
JF - Tuberculosis and Respiratory Diseases
SN - 1738-3536
IS - 3
ER -