TY - JOUR
T1 - Endometriosis Is Associated with Adverse Pregnancy Outcomes
T2 - a National Population-Based Study
AU - Yi, Kyong Wook
AU - Cho, Geum Joon
AU - Park, Keon Vin
AU - Han, Sung Won
AU - Shin, Jung Ho
AU - Kim, Tak
AU - Hur, Jun Young
N1 - Publisher Copyright:
© 2019, Society for Reproductive Investigation.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/5/1
Y1 - 2020/5/1
N2 - Pregnancy and neonatal outcomes in women diagnosed with endometriosis were investigated using data collected from the Korea National Health Insurance Claims Database and the National Health Screening Program for Infants and Children. A total of 3,778,561 women who gave birth between 2007 and 2015 were identified, and 1,938,424 primiparous women and their newborns were included in this study. Women with a diagnosis of endometriosis had a significantly higher incidence of multiple pregnancy, cesarean section, breech presentation, postpartum hemorrhage, placental abruption, placenta previa, and stillbirth than women without endometriosis (P < 0.0001). The rates of preterm birth and low birth weight were also increased in women with endometriosis (P < 0.0001). After adjusting for age, the estimated risks of these outcomes remained significant. Women previously diagnosed with endometriosis have an increased risk of adverse pregnancy and neonatal outcomes. Particular attention and information regarding these conditions should be provided to women with endometriosis during the preconception or antenatal periods.
AB - Pregnancy and neonatal outcomes in women diagnosed with endometriosis were investigated using data collected from the Korea National Health Insurance Claims Database and the National Health Screening Program for Infants and Children. A total of 3,778,561 women who gave birth between 2007 and 2015 were identified, and 1,938,424 primiparous women and their newborns were included in this study. Women with a diagnosis of endometriosis had a significantly higher incidence of multiple pregnancy, cesarean section, breech presentation, postpartum hemorrhage, placental abruption, placenta previa, and stillbirth than women without endometriosis (P < 0.0001). The rates of preterm birth and low birth weight were also increased in women with endometriosis (P < 0.0001). After adjusting for age, the estimated risks of these outcomes remained significant. Women previously diagnosed with endometriosis have an increased risk of adverse pregnancy and neonatal outcomes. Particular attention and information regarding these conditions should be provided to women with endometriosis during the preconception or antenatal periods.
KW - Endometriosis
KW - Neonatal outcome
KW - Pregnancy outcome
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U2 - 10.1007/s43032-019-00109-1
DO - 10.1007/s43032-019-00109-1
M3 - Article
C2 - 31953772
AN - SCOPUS:85079673326
VL - 27
SP - 1175
EP - 1180
JO - Reproductive Sciences
JF - Reproductive Sciences
SN - 1933-7191
IS - 5
ER -