Endometriosis Is Associated with Adverse Pregnancy Outcomes: a National Population-Based Study

Research output: Contribution to journalArticle


Pregnancy and neonatal outcomes in women diagnosed with endometriosis were investigated using data collected from the Korea National Health Insurance Claims Database and the National Health Screening Program for Infants and Children. A total of 3,778,561 women who gave birth between 2007 and 2015 were identified, and 1,938,424 primiparous women and their newborns were included in this study. Women with a diagnosis of endometriosis had a significantly higher incidence of multiple pregnancy, cesarean section, breech presentation, postpartum hemorrhage, placental abruption, placenta previa, and stillbirth than women without endometriosis (P < 0.0001). The rates of preterm birth and low birth weight were also increased in women with endometriosis (P < 0.0001). After adjusting for age, the estimated risks of these outcomes remained significant. Women previously diagnosed with endometriosis have an increased risk of adverse pregnancy and neonatal outcomes. Particular attention and information regarding these conditions should be provided to women with endometriosis during the preconception or antenatal periods.

Original languageEnglish
JournalReproductive Sciences
Publication statusAccepted/In press - 2020 Jan 1


  • Endometriosis
  • Neonatal outcome
  • Pregnancy outcome

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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