Endoscopic diagnosis of colorectal serrated lesions: Current status and future perspectives based on the results of a questionnaire survey

Takahisa Matsuda, Shiro Oka, Hiroaki Ikematsu, Hiro O. Matsushita, Yuichi Mori, Yoji Takeuchi, Naoto Tamai, Takuji Kawamura, Akiko Chino, Bora Keum, Supakij Khomvilai, Toshio Uraoka

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Serrated lesions, especially sessile serrated adenoma/polyps (SSA/P) are considered one of the most important precursors of colorectal cancers. However, it is still difficult to endoscopically differentiate SSA/P from hyperplastic polyps. In the present review, we mainly focus on the current status and future perspectives of endoscopic diagnosis of colorectal serrated lesions based on the results of a questionnaire survey and report from the Endoscopic Forum Japan (EFJ) 2015 held in Tokyo in August 2015. The proposed diagnostic strategy recommended for colorectal serrated lesions is as follows. (i) For detection, use of an updated image-enhanced endoscopy system including autofluorescence imaging (AFI) and narrow-band imaging (NBI) may be promising. (ii) For differential diagnosis (hyperplastic polyp or SSA/P) of diminutive, small and large serrated lesions, NBI with magnification and magnifying chromoendoscopy using both indigocarmine and crystal violet should be applied, respectively. (iii) For differential diagnosis of SSA/P (with or without cytological dysplasia), magnifying chromoendoscopy, endocytoscopy and updated AFI system modalities might be promising.

Original languageEnglish
Pages (from-to)35-42
Number of pages8
JournalDigestive Endoscopy
Volume28
DOIs
Publication statusPublished - 2016 Apr 1

    Fingerprint

Keywords

  • colonoscopy
  • endoscopic diagnosis
  • image-enhanced endoscopy
  • serrated lesion
  • sessile serrated adenoma/polyp (SSA/P)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Matsuda, T., Oka, S., Ikematsu, H., Matsushita, H. O., Mori, Y., Takeuchi, Y., Tamai, N., Kawamura, T., Chino, A., Keum, B., Khomvilai, S., & Uraoka, T. (2016). Endoscopic diagnosis of colorectal serrated lesions: Current status and future perspectives based on the results of a questionnaire survey. Digestive Endoscopy, 28, 35-42. https://doi.org/10.1111/den.12632