Endoscopic findings around the gastroesophageal junction: An experience from a tertiary hospital in Korea

Ji Hyun Kim, Jin Ki Hwang, Juhyung Kim, Sehe Dong Lee, Beom Jae Lee, Jae Seon Kim, Young Tae Bak

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)

    Abstract

    Background/Aims: Important lesions related to gastroesophageal reflux disease (GERD) are located around the gastroesophageal junction (GEJ). This study examined the distribution of endoscopic findings around the GEJ and elucidated their relationship to each other and esophageal manometric features. Methods: Endoscopic data were collected prospectively from 2,450 consecutive diagnostic upper gastrointestinal endoscopies. The presence and degree of hiatal hernia (HH), columnar-lined esophagus (CLE), and reflux esophagitis (RE) were recorded. Esophageal manometric data were collected from 181 patients. Results: The prevalence of HH, CLE, and RE was 9.8, 18.8, and 9.9%, respectively. Of all HH and CLE cases, 62.8 and 98.9%, respectively, were of the short-segment variety. Of all RE cases, 95.0% were mild. Younger age, male gender, the presence of HH, and a higher gastroesophageal flap valve (GEFV) grades were associated with the presence of RE. Increased ZAP grades were associated with increased prevalence and grades of HH, CLE, and RE. Higher GEFV grades were associated with increased prevalence and grades of HH, CLE, and RE. Lower esophageal sphincter pressure (LESP) decreased in patients with HH or RE compared to those without HH or RE. Conclusions: Endoscopic findings around the GEJ revealed that a substantial proportion of our patients showed features potentially related to GERD. In combination with other recent reports, our study implies that Korea is no longer a very-low-prevalence area of GERD, although it may predominate in silent or milder forms.

    Original languageEnglish
    Pages (from-to)127-133
    Number of pages7
    JournalKorean Journal of Internal Medicine
    Volume23
    Issue number3
    DOIs
    Publication statusPublished - 2008 Sep

    Keywords

    • Columnar-lined esophagus
    • Gastroesophageal flap valve
    • Hiatal hernia
    • Reflux esophagitis
    • Z-line appearance

    ASJC Scopus subject areas

    • Internal Medicine

    Fingerprint

    Dive into the research topics of 'Endoscopic findings around the gastroesophageal junction: An experience from a tertiary hospital in Korea'. Together they form a unique fingerprint.

    Cite this