Abstract
Background: Symptomatic or significant vascular lesions of Takayasu arteritis (TA) need interventions. Although percutaneous transluminal angioplasty with balloon is a less invasive and safe method, stent implantation in TA can be an alternative option. However, superiority between balloon angioplasty and stenting in TA is not conclusive. Methods: A meta-analysis comparing balloon angioplasty and stenting outcomes was performed using the MEDLINE and EMBASE databases. Results: A total of 7 studies on 266 patients and 316 lesions were included. Balloon angioplasty was performed in 186 lesions and stenting in 130 lesions. There were no significant differences in the incidence of both restenosis and other complications between balloon angioplasty and stenting [odds ratio (OR)=2.39, 95% confidence interval (CI)=0.66-8.66, P=.18; OR=1.80, 95% CI=0.49-6.65, P=.38, respectively]. In the renal arteries, the risk of restenosis in stenting was significantly higher than that in balloon angioplasty (OR=4.40, 95% CI=2.14-9.02, P<.001). The clinical efficacy of improving renal hypertension between balloon angioplasty and stenting at the renal artery lesions was similar (OR=0.65, 95% CI=0.28-1.51, P=.31); however, acute vascular complications were significantly fewer in stenting than in balloon angioplasty (OR=0.07, 95% CI=0.02-0.29, P<.001). Conclusion: This meta-analysis found that balloon angioplasty can yield better results in renal artery interventions than stenting. Nonetheless, it is desirable to avoid vessel dissections during balloon angioplasty, which can eventually require stent implantations.
| Original language | English |
|---|---|
| Article number | e7558 |
| Journal | Medicine (United States) |
| Volume | 96 |
| Issue number | 29 |
| DOIs | |
| Publication status | Published - 2017 Jul 1 |
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Keywords
- balloon angioplasty
- complication
- restenosis
- stent implantation
- Takayasu arteritis
ASJC Scopus subject areas
- Medicine(all)
Cite this
Endovascular balloon angioplasty versus stenting in patients with Takayasu arteritis. / Jeong, Han Saem; Jung, Jae Hyun; Song, Gwan Gyu; Choi, Sungjae; Hong, Soon Jun.
In: Medicine (United States), Vol. 96, No. 29, e7558, 01.07.2017.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Endovascular balloon angioplasty versus stenting in patients with Takayasu arteritis
AU - Jeong, Han Saem
AU - Jung, Jae Hyun
AU - Song, Gwan Gyu
AU - Choi, Sungjae
AU - Hong, Soon Jun
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Background: Symptomatic or significant vascular lesions of Takayasu arteritis (TA) need interventions. Although percutaneous transluminal angioplasty with balloon is a less invasive and safe method, stent implantation in TA can be an alternative option. However, superiority between balloon angioplasty and stenting in TA is not conclusive. Methods: A meta-analysis comparing balloon angioplasty and stenting outcomes was performed using the MEDLINE and EMBASE databases. Results: A total of 7 studies on 266 patients and 316 lesions were included. Balloon angioplasty was performed in 186 lesions and stenting in 130 lesions. There were no significant differences in the incidence of both restenosis and other complications between balloon angioplasty and stenting [odds ratio (OR)=2.39, 95% confidence interval (CI)=0.66-8.66, P=.18; OR=1.80, 95% CI=0.49-6.65, P=.38, respectively]. In the renal arteries, the risk of restenosis in stenting was significantly higher than that in balloon angioplasty (OR=4.40, 95% CI=2.14-9.02, P<.001). The clinical efficacy of improving renal hypertension between balloon angioplasty and stenting at the renal artery lesions was similar (OR=0.65, 95% CI=0.28-1.51, P=.31); however, acute vascular complications were significantly fewer in stenting than in balloon angioplasty (OR=0.07, 95% CI=0.02-0.29, P<.001). Conclusion: This meta-analysis found that balloon angioplasty can yield better results in renal artery interventions than stenting. Nonetheless, it is desirable to avoid vessel dissections during balloon angioplasty, which can eventually require stent implantations.
AB - Background: Symptomatic or significant vascular lesions of Takayasu arteritis (TA) need interventions. Although percutaneous transluminal angioplasty with balloon is a less invasive and safe method, stent implantation in TA can be an alternative option. However, superiority between balloon angioplasty and stenting in TA is not conclusive. Methods: A meta-analysis comparing balloon angioplasty and stenting outcomes was performed using the MEDLINE and EMBASE databases. Results: A total of 7 studies on 266 patients and 316 lesions were included. Balloon angioplasty was performed in 186 lesions and stenting in 130 lesions. There were no significant differences in the incidence of both restenosis and other complications between balloon angioplasty and stenting [odds ratio (OR)=2.39, 95% confidence interval (CI)=0.66-8.66, P=.18; OR=1.80, 95% CI=0.49-6.65, P=.38, respectively]. In the renal arteries, the risk of restenosis in stenting was significantly higher than that in balloon angioplasty (OR=4.40, 95% CI=2.14-9.02, P<.001). The clinical efficacy of improving renal hypertension between balloon angioplasty and stenting at the renal artery lesions was similar (OR=0.65, 95% CI=0.28-1.51, P=.31); however, acute vascular complications were significantly fewer in stenting than in balloon angioplasty (OR=0.07, 95% CI=0.02-0.29, P<.001). Conclusion: This meta-analysis found that balloon angioplasty can yield better results in renal artery interventions than stenting. Nonetheless, it is desirable to avoid vessel dissections during balloon angioplasty, which can eventually require stent implantations.
KW - balloon angioplasty
KW - complication
KW - restenosis
KW - stent implantation
KW - Takayasu arteritis
UR - http://www.scopus.com/inward/record.url?scp=85026422554&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85026422554&partnerID=8YFLogxK
U2 - 10.1097/MD.0000000000007558
DO - 10.1097/MD.0000000000007558
M3 - Review article
C2 - 28723782
AN - SCOPUS:85026422554
VL - 96
JO - Medicine; analytical reviews of general medicine, neurology, psychiatry, dermatology, and pediatries
JF - Medicine; analytical reviews of general medicine, neurology, psychiatry, dermatology, and pediatries
SN - 0025-7974
IS - 29
M1 - e7558
ER -