Engineered polymers for advanced drug delivery

Sungwon Kim, Jong Ho Kim, Oju Jeon, Ick Chan Kwon, Kinam Park

Research output: Contribution to journalReview article

251 Citations (Scopus)

Abstract

Engineered polymers have been utilized for developing advanced drug delivery systems. The development of such polymers has caused advances in polymer chemistry, which, in turn, has resulted in smart polymers that can respond to changes in environmental condition such as temperature, pH, and biomolecules. The responses vary widely from swelling/deswelling to degradation. Drug-polymer conjugates and drug-containing nano/micro-particles have been used for drug targeting. Engineered polymers and polymeric systems have also been used in new areas, such as molecular imaging as well as in nanotechnology. This review examines the engineered polymers that have been used as traditional drug delivery systems and as more recent applications in nanotechnology.

Original languageEnglish
Pages (from-to)420-430
Number of pages11
JournalEuropean Journal of Pharmaceutics and Biopharmaceutics
Volume71
Issue number3
DOIs
Publication statusPublished - 2009 Mar

Keywords

  • Controlled release
  • Drug delivery
  • Drug targeting
  • Molecular imaging
  • Smart polymer

ASJC Scopus subject areas

  • Biotechnology
  • Pharmaceutical Science

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