Engineering insect flight metabolics using immature stage implanted microfluidics

Aram Chung, David Erickson

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Small-scale insect inspired aircraft represent a promising approach to downscaling traditional aircraft designs. Despite advancements in microfabrication, however, it has proven difficult to fully replicate the mechanical complexities that enable these natural systems. As an alternative, recent efforts have used implanted electrical, optical or acoustic microsystems to exert direct control over insect flight. Here we demonstrate, for the first time, a method of directly and reversibly engineering insect flight metabolics using immature stage implanted microfluidics. We present our technique and device for on-command modulation of the internal levels of l-glutamic and l-aspartate acids and quantify the resulting changes in metabolic activity by monitoring respiratory CO 2 output. Microfluidic devices implanted 1 to 2 days prior to insects' emergence achieved survivability and flight-capable rates of 96% and 36%, respectively. Behavior ranging from retarded motion to complete, reversible paralysis, over timescales ranging from minutes to hours is demonstrated.

Original languageEnglish
Pages (from-to)669-676
Number of pages8
JournalLab on a Chip
Volume9
Issue number5
DOIs
Publication statusPublished - 2009 Jan 1
Externally publishedYes

Fingerprint

Microfluidics
Aircraft
Lab-On-A-Chip Devices
Insects
Microtechnology
Insect Control
Hemiptera
Microfabrication
Microsystems
Carbon Monoxide
Acoustics
Aspartic Acid
Paralysis
Modulation
Equipment and Supplies
Acids
Monitoring

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

Cite this

Engineering insect flight metabolics using immature stage implanted microfluidics. / Chung, Aram; Erickson, David.

In: Lab on a Chip, Vol. 9, No. 5, 01.01.2009, p. 669-676.

Research output: Contribution to journalArticle

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