Enhanced oxidative damage to DNA, lipids, and proteins and levels of some antioxidant enzymes, cytokines, and heat shock proteins in patients infected with influenza H1N1 virus

J. Y. Lim, E. Oh, Y. Kim, W. W. Jung, H. S. Kim, J. Lee, Dong Geun Sul

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Overweight and obesity is becoming widespread enough to generate an acceptable and misleading social status. By 2030, in the USA up to 86 % of adults will be overweight or obese. Some selected statistical data based on the body mass index (BMI) indicated that overweight was not associated with increased mortality, this provoked a conceivable interest. Added to this is the observation that while the prevalence of obesity is dramatically increasing, the cardiovascular mortality and life expectancy in the European Union and USA has improved. When more sensitive indicators of body adiposity and its distribution than the BMI, like the waist-thigh ratio in both sexes and the waist-hip ratio in women are projected on mortality, it becomes obvious that even overweight is associated with an increased health risk. Gaining excessive body fat is a continuous, frequently progressive process. Present obesity epidemic in childhood will manifest with deleterious consequences only in future years when adolescents reach adulthood. Prevention is thus essential even before the overweight sets in. Improved life expectancy observed in large populations despite obesity epidemic, is a favourable medical success in the management of hypertension, of serum lipid disorders and diabetes. While encouraging, when it is observed in large population, it does not take away the potential health risk of a metabolic disorder in an individual who is overweight (Fig. 7, Ref. 25).

Original languageEnglish
Pages (from-to)253-260
Number of pages8
JournalActa Virologica
Volume58
Issue number3
Publication statusPublished - 2014

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H1N1 Subtype Influenza A Virus
Heat-Shock Proteins
Orthomyxoviridae
DNA Damage
Antioxidants
Cytokines
Lipids
Enzymes
Proteins
Obesity
Life Expectancy
Mortality
Body Mass Index
Waist-Hip Ratio
Pediatric Obesity
Adiposity
Health
European Union
Thigh
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Enhanced oxidative damage to DNA, lipids, and proteins and levels of some antioxidant enzymes, cytokines, and heat shock proteins in patients infected with influenza H1N1 virus. / Lim, J. Y.; Oh, E.; Kim, Y.; Jung, W. W.; Kim, H. S.; Lee, J.; Sul, Dong Geun.

In: Acta Virologica, Vol. 58, No. 3, 2014, p. 253-260.

Research output: Contribution to journalArticle

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