Enhancement of anti-complementary and radical scavenging activities in the submerged culture of Cordyceps sinensis by addition of citrus peel

Jang Won Choi, Kyung Soo Ra, Seong Yeong Kim, Taek Joon Yoon, Kwang W. Yu, Kwang Soon Shin, Sam Pin Lee, Hyung Joo Suh

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

To investigate the optimal conditions for the production of Cordyceps sinensis by the submerged culture method, glucosamine and exopolysaccharide (EPS) productivities were determined in culture broth containing different carbon sources, principally rice bran and citrus peel. An optimal medium composition (1.5% rice bran, 0.5% molasses, 3% CSL, 0.1% KH2PO4, and 0.05% MgSO4) and the optimal condition (25 °C and 5-6 d culture time) for high EPS productivity with potent immune-stimulating activities were obtained. The addition of citrus peel to the culture of C. sinensis under the optimized conditions improved EPS productivity and glucosamine content. Furthermore, anti-complementary activity was higher (58.0-80.8%) using citrus peel as compared to no addition of citrus peel (48.2-68.7%). Antioxidant activity (AEAC value) of the citrus peel culture was high (284.3-384.6 mg/100 g) compared to that of the culture without citrus peel (142.8-219.5 mg/100 g), indicating that the citrus peel helped enhance the anti-complementary and antioxidant activities of C. sinensis.

Original languageEnglish
Pages (from-to)6028-6034
Number of pages7
JournalBioresource Technology
Volume101
Issue number15
DOIs
Publication statusPublished - 2010 Aug 1

Fingerprint

Scavenging
Glucosamine
Productivity
Antioxidants
productivity
antioxidant
Molasses
rice
Carbon
Chemical analysis
carbon

Keywords

  • Anti-complementary activity
  • Antioxidant activity
  • Citrus peel
  • Cordyceps sinensis
  • Exopolysaccharide

ASJC Scopus subject areas

  • Bioengineering
  • Environmental Engineering
  • Waste Management and Disposal

Cite this

Enhancement of anti-complementary and radical scavenging activities in the submerged culture of Cordyceps sinensis by addition of citrus peel. / Choi, Jang Won; Ra, Kyung Soo; Kim, Seong Yeong; Yoon, Taek Joon; Yu, Kwang W.; Shin, Kwang Soon; Lee, Sam Pin; Suh, Hyung Joo.

In: Bioresource Technology, Vol. 101, No. 15, 01.08.2010, p. 6028-6034.

Research output: Contribution to journalArticle

Choi, Jang Won ; Ra, Kyung Soo ; Kim, Seong Yeong ; Yoon, Taek Joon ; Yu, Kwang W. ; Shin, Kwang Soon ; Lee, Sam Pin ; Suh, Hyung Joo. / Enhancement of anti-complementary and radical scavenging activities in the submerged culture of Cordyceps sinensis by addition of citrus peel. In: Bioresource Technology. 2010 ; Vol. 101, No. 15. pp. 6028-6034.
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