TY - JOUR
T1 - Environmental factors which can affect the burden of pneumococcal disease and the immune response to pneumococcal vaccines
T2 - the need for more precisely delineated vaccine recommendations
AU - Park, Seong Beom
AU - Kim, Hyun Jin
AU - Cheong, Hee Jin
N1 - Funding Information:
A reviewer of this manuscript declares receiving grant funding from Merck & Co. Inc. and Pfizer. Another reviewer of this manuscript declares receiving honorarium from Pfizer, GlaxoSmithKline and Merck for advisory boards on pneumococcal vaccines as well as receiving funding from Pfizer and Merck for a project related to Streptococcus pneumoniae. Peer reviewers on this manuscript have no other relevant financial or other relationships to disclose.
Funding Information:
Under the direction of the authors, medical writing assistance was provided by David P. Figgitt, ISMPP CMPP™, Content Ed Net, with funding from Pfizer Pharmaceuticals Korea Ltd., Seoul, Republic of Korea.
Publisher Copyright:
© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2019/6/3
Y1 - 2019/6/3
N2 - Introduction: Precision medicine describes the customization of healthcare tailored to the individual patient. Generally, vaccines are considered as public health tools rather than from the individual patient perspective. However, adult vaccination programs in particular should consider many different factors, at the individual level and also from societal, cultural and country-specific perspectives. Currently, most immunization programs, including those for pneumococcal vaccines, have only been adopted on the basis of age or medical risk. Areas covered: Based on a broad literature search, this review addresses possible environmental factors which can affect the burden of pneumococcal disease and the immune response to pneumococcal vaccines. Expert opinion: Factors which influence the incidence of pneumococcal disease and the reaction against pneumococcal vaccination, including personal conditions, geographic/ethnic factors and social risks, are diverse. To maximize the effects of pneumococcal vaccination, not only for public health but also to induce optimal effects at the individual level, vaccines need to be verified under diverse situations and with collaboration among relevant medical societies, governments, and the pharmaceutical industry. Whereas vaccines are generally considered only from the public health perspective, flexible, comprehensive and tailored pneumococcal immunization programs, with appropriate policy support, can generate a greater positive impact on public health.
AB - Introduction: Precision medicine describes the customization of healthcare tailored to the individual patient. Generally, vaccines are considered as public health tools rather than from the individual patient perspective. However, adult vaccination programs in particular should consider many different factors, at the individual level and also from societal, cultural and country-specific perspectives. Currently, most immunization programs, including those for pneumococcal vaccines, have only been adopted on the basis of age or medical risk. Areas covered: Based on a broad literature search, this review addresses possible environmental factors which can affect the burden of pneumococcal disease and the immune response to pneumococcal vaccines. Expert opinion: Factors which influence the incidence of pneumococcal disease and the reaction against pneumococcal vaccination, including personal conditions, geographic/ethnic factors and social risks, are diverse. To maximize the effects of pneumococcal vaccination, not only for public health but also to induce optimal effects at the individual level, vaccines need to be verified under diverse situations and with collaboration among relevant medical societies, governments, and the pharmaceutical industry. Whereas vaccines are generally considered only from the public health perspective, flexible, comprehensive and tailored pneumococcal immunization programs, with appropriate policy support, can generate a greater positive impact on public health.
KW - Environmental factors
KW - PCV13
KW - PPSV23
KW - pneumococcal vaccine
KW - pneumovax
KW - prevnar
UR - http://www.scopus.com/inward/record.url?scp=85068036888&partnerID=8YFLogxK
U2 - 10.1080/14760584.2019.1607303
DO - 10.1080/14760584.2019.1607303
M3 - Review article
C2 - 30998430
AN - SCOPUS:85068036888
VL - 18
SP - 587
EP - 596
JO - Expert Review of Vaccines
JF - Expert Review of Vaccines
SN - 1476-0584
IS - 6
ER -