Enzymatic 'charging' of synthetic polymers

Jingyi Rao, Anzar Khan

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Actuated by an enzyme, a purely synthetic and chemically neutral polymer chain transforms into a chemically charged cationic structure. This biologically triggered structural change enables the polymer chain to recognize a negatively charged biomolecule (RNA) through electrostatic interactions in aqueous environment. The supramolecular recognition event ultimately leads to the assembly of oppositely charged, artificial and natural polymer chains, into the polyion complex-based nanoparticles.

Original languageEnglish
Pages (from-to)686-690
Number of pages5
JournalPolymer Chemistry
Volume6
Issue number5
DOIs
Publication statusPublished - 2015 Feb 7

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Polymers and Plastics
  • Organic Chemistry

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