Enzymatic 'charging' of synthetic polymers

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Actuated by an enzyme, a purely synthetic and chemically neutral polymer chain transforms into a chemically charged cationic structure. This biologically triggered structural change enables the polymer chain to recognize a negatively charged biomolecule (RNA) through electrostatic interactions in aqueous environment. The supramolecular recognition event ultimately leads to the assembly of oppositely charged, artificial and natural polymer chains, into the polyion complex-based nanoparticles.

Original languageEnglish
Pages (from-to)686-690
Number of pages5
JournalPolymer Chemistry
Volume6
Issue number5
DOIs
Publication statusPublished - 2015 Feb 7
Externally publishedYes

Fingerprint

Polymers
Natural polymers
Biomolecules
Coulomb interactions
RNA
Enzymes
Nanoparticles
Static Electricity

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Polymers and Plastics
  • Organic Chemistry

Cite this

Enzymatic 'charging' of synthetic polymers. / Rao, Jingyi; Khan, Anzar.

In: Polymer Chemistry, Vol. 6, No. 5, 07.02.2015, p. 686-690.

Research output: Contribution to journalArticle

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