Enzyme stabilization in various nanostructured materials

Byoung Chan Kim, Jungbae Kim, Seong H. Kim, Taeghwan Hyeon, Man Bock Gu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Efforts using nanostructured materials are an intriguing approach for developing composite of enzyme-nanomaterials since these materials can provide a large surface area, which can lead high volumetric enzyme activity. Recent advances in enzyme aggregation via cross-linking are promising for the development of highly stable catalytic composite of bio-nanomaterials. Significant enhancement of enzyme stabilization was realized as introducing cross-linked enzyme aggregates (CLEAs) via glutaraldehyde mediated coupling with various nanostructured materials such as nanofiber, carbon nanotube, or mesoporous silica. The enzyme stability of enzyme aggregated nanomaterials was greatly enhanced with essentially no measurable loss of activity over a month or several days of observation under rigorous shaking condition. This approach of enzyme aggregation with various nanostructure materials, yielding high activity and stability, creates a useful new biocatalytic immobilized enzyme system with potential applications in biosensor, bioelectrochemistry, bioremediation and bioconversion.

Original languageEnglish
Title of host publicationAIChE Annual Meeting, Conference Proceedings
Publication statusPublished - 2005 Dec 1
Event05AIChE: 2005 AIChE Annual Meeting and Fall Showcase - Cincinnati, OH, United States
Duration: 2005 Oct 302005 Nov 4

Other

Other05AIChE: 2005 AIChE Annual Meeting and Fall Showcase
CountryUnited States
CityCincinnati, OH
Period05/10/3005/11/4

Fingerprint

Nanostructured materials
Enzymes
Stabilization
Agglomeration
Bioconversion
Bioremediation
Composite materials
Enzyme activity
Nanofibers
Biosensors
Nanostructures
Carbon nanotubes
Silica

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Kim, B. C., Kim, J., Kim, S. H., Hyeon, T., & Gu, M. B. (2005). Enzyme stabilization in various nanostructured materials. In AIChE Annual Meeting, Conference Proceedings

Enzyme stabilization in various nanostructured materials. / Kim, Byoung Chan; Kim, Jungbae; Kim, Seong H.; Hyeon, Taeghwan; Gu, Man Bock.

AIChE Annual Meeting, Conference Proceedings. 2005.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kim, BC, Kim, J, Kim, SH, Hyeon, T & Gu, MB 2005, Enzyme stabilization in various nanostructured materials. in AIChE Annual Meeting, Conference Proceedings. 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Cincinnati, OH, United States, 05/10/30.
Kim BC, Kim J, Kim SH, Hyeon T, Gu MB. Enzyme stabilization in various nanostructured materials. In AIChE Annual Meeting, Conference Proceedings. 2005
Kim, Byoung Chan ; Kim, Jungbae ; Kim, Seong H. ; Hyeon, Taeghwan ; Gu, Man Bock. / Enzyme stabilization in various nanostructured materials. AIChE Annual Meeting, Conference Proceedings. 2005.
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