Eosinophilic gastrointestinal disorder presenting as intractable vomiting and ascites in a young girl

Ji Yoon Kwon, Ji Sun Huh, Bo-Kyung Je, Kwang Dae Hong, Jee Hyun Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Eosinophilic gastrointestinal disorder (EGID) is a rare disease in children that affects the bowel wall, with eosinophilic infiltration in the absence of any other causes for eosinophilia. The etiology remains unknown, but allergies and immunological imbalance are suspected triggers. We encountered a case of serosal EGID presenting as intractable vomiting and ascites in a 9-year-old girl, after influenza virus infection. Peripheral eosinophilia was not present. The diagnosis was confirmed by biopsy of the bowel wall through laparotomy and endoscopy, and controlled by 2 courses of steroid therapy due to recurring symptoms. Influenza virus infection was assumed to play a role in the onset of EGID through a Th2 response that stimulated eosinophilic infiltration in the GI tract. We therefore report this case along with a literature review.

Original languageEnglish
Article number198
JournalPediatric Gastroenterology, Hepatology and Nutrition
Volume20
Issue number3
DOIs
Publication statusPublished - 2017 Jan 1

Fingerprint

Eosinophilia
Virus Diseases
Orthomyxoviridae
Ascites
Vomiting
Rare Diseases
Laparotomy
Endoscopy
Gastrointestinal Tract
Hypersensitivity
Steroids
Biopsy
Therapeutics

Keywords

  • Eosinophilic enteropathy
  • Influenza A viruses
  • Serous membrane

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hepatology
  • Gastroenterology

Cite this

Eosinophilic gastrointestinal disorder presenting as intractable vomiting and ascites in a young girl. / Kwon, Ji Yoon; Huh, Ji Sun; Je, Bo-Kyung; Hong, Kwang Dae; Lee, Jee Hyun.

In: Pediatric Gastroenterology, Hepatology and Nutrition, Vol. 20, No. 3, 198, 01.01.2017.

Research output: Contribution to journalArticle

@article{33ff4f54c3484a068e02bdf30ae1d9e8,
title = "Eosinophilic gastrointestinal disorder presenting as intractable vomiting and ascites in a young girl",
abstract = "Eosinophilic gastrointestinal disorder (EGID) is a rare disease in children that affects the bowel wall, with eosinophilic infiltration in the absence of any other causes for eosinophilia. The etiology remains unknown, but allergies and immunological imbalance are suspected triggers. We encountered a case of serosal EGID presenting as intractable vomiting and ascites in a 9-year-old girl, after influenza virus infection. Peripheral eosinophilia was not present. The diagnosis was confirmed by biopsy of the bowel wall through laparotomy and endoscopy, and controlled by 2 courses of steroid therapy due to recurring symptoms. Influenza virus infection was assumed to play a role in the onset of EGID through a Th2 response that stimulated eosinophilic infiltration in the GI tract. We therefore report this case along with a literature review.",
keywords = "Eosinophilic enteropathy, Influenza A viruses, Serous membrane",
author = "Kwon, {Ji Yoon} and Huh, {Ji Sun} and Bo-Kyung Je and Hong, {Kwang Dae} and Lee, {Jee Hyun}",
year = "2017",
month = "1",
day = "1",
doi = "10.5223/pghn.2017.20.3.198",
language = "English",
volume = "20",
journal = "Pediatric Gastroenterology, Hepatology and Nutrition",
issn = "2234-8646",
publisher = "Korean Society of Pediartic Gastroenterology, Hepatology and Nutrition",
number = "3",

}

TY - JOUR

T1 - Eosinophilic gastrointestinal disorder presenting as intractable vomiting and ascites in a young girl

AU - Kwon, Ji Yoon

AU - Huh, Ji Sun

AU - Je, Bo-Kyung

AU - Hong, Kwang Dae

AU - Lee, Jee Hyun

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Eosinophilic gastrointestinal disorder (EGID) is a rare disease in children that affects the bowel wall, with eosinophilic infiltration in the absence of any other causes for eosinophilia. The etiology remains unknown, but allergies and immunological imbalance are suspected triggers. We encountered a case of serosal EGID presenting as intractable vomiting and ascites in a 9-year-old girl, after influenza virus infection. Peripheral eosinophilia was not present. The diagnosis was confirmed by biopsy of the bowel wall through laparotomy and endoscopy, and controlled by 2 courses of steroid therapy due to recurring symptoms. Influenza virus infection was assumed to play a role in the onset of EGID through a Th2 response that stimulated eosinophilic infiltration in the GI tract. We therefore report this case along with a literature review.

AB - Eosinophilic gastrointestinal disorder (EGID) is a rare disease in children that affects the bowel wall, with eosinophilic infiltration in the absence of any other causes for eosinophilia. The etiology remains unknown, but allergies and immunological imbalance are suspected triggers. We encountered a case of serosal EGID presenting as intractable vomiting and ascites in a 9-year-old girl, after influenza virus infection. Peripheral eosinophilia was not present. The diagnosis was confirmed by biopsy of the bowel wall through laparotomy and endoscopy, and controlled by 2 courses of steroid therapy due to recurring symptoms. Influenza virus infection was assumed to play a role in the onset of EGID through a Th2 response that stimulated eosinophilic infiltration in the GI tract. We therefore report this case along with a literature review.

KW - Eosinophilic enteropathy

KW - Influenza A viruses

KW - Serous membrane

UR - http://www.scopus.com/inward/record.url?scp=85032257236&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032257236&partnerID=8YFLogxK

U2 - 10.5223/pghn.2017.20.3.198

DO - 10.5223/pghn.2017.20.3.198

M3 - Article

AN - SCOPUS:85032257236

VL - 20

JO - Pediatric Gastroenterology, Hepatology and Nutrition

JF - Pediatric Gastroenterology, Hepatology and Nutrition

SN - 2234-8646

IS - 3

M1 - 198

ER -