Eosinophilic gastrointestinal disorder presenting as intractable vomiting and ascites in a young girl

Ji Yoon Kwon, Ji Sun Huh, Bo-Kyung Je, Kwang Dae Hong, Jee Hyun Lee

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Eosinophilic gastrointestinal disorder (EGID) is a rare disease in children that affects the bowel wall, with eosinophilic infiltration in the absence of any other causes for eosinophilia. The etiology remains unknown, but allergies and immunological imbalance are suspected triggers. We encountered a case of serosal EGID presenting as intractable vomiting and ascites in a 9-year-old girl, after influenza virus infection. Peripheral eosinophilia was not present. The diagnosis was confirmed by biopsy of the bowel wall through laparotomy and endoscopy, and controlled by 2 courses of steroid therapy due to recurring symptoms. Influenza virus infection was assumed to play a role in the onset of EGID through a Th2 response that stimulated eosinophilic infiltration in the GI tract. We therefore report this case along with a literature review.

Original languageEnglish
Article number198
JournalPediatric Gastroenterology, Hepatology and Nutrition
Volume20
Issue number3
DOIs
Publication statusPublished - 2017 Jan 1

Keywords

  • Eosinophilic enteropathy
  • Influenza A viruses
  • Serous membrane

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hepatology
  • Gastroenterology

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