Erectile dysfunction and disease-specific quality of life in patients with obstructive sleep apnea

H. W. Shin, Yoon Chan Rah, D. H. Han, S. Chung, I. Y. Yoon, C. S. Rhee, C. H. Lee, Y. G. Min, D. Y. Kim

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Several reports have suggested a high incidence of erectile dysfunction (ED) among patients with obstructive sleep apnea syndrome (OSAS). The aim of this study was to investigate the correlation between OSAS and ED, or disease-specific quality of life (QOL) in patients with OSAS. In addition, we analyzed specific polysomnographic (PSG) parameters in predicting ED in OSAS patients. In total, 32 patients with OSAS and 27 normal controls were asked to complete the Korean versions of the International Index of Erectile Function questionnaire (KIIEF-5) and the Calgary Sleep Apnea Quality of Life Index (SAQLI). All patients then underwent a full-night in-laboratory PSG examination. Patients were diagnosed with OSAS if they had clinical symptoms suggestive of OSAS for at least 1 year and an apnea-hypopnea index (AHI) of more than 10 in PSG. Nineteen patients (59.3%) in the OSAS group showed ED, which was significantly higher than in the control group (8 patients, 29.6%, P=0.012). In addition, SAQLI scores worsened as AHI increased (r=0.327, P=0.011) and as the lowest oxygen saturation level decreased (r=0.420, P=0.001). ED was not significantly correlated with AHI (r=0.061, P=0.649); however, it was significantly correlated with the lowest oxygen saturation decreased (r=0.338, P=0.009). When the cutoff value for the lowest oxygen saturation level to predict ED was set at 77%, its positive predictive value was 88.9% (sensitivity=0.70, specificity=0.62). Thus, all male patients with OSAS should be screened for erectile dysfunction and more comprehensive consultation is needed, especially, if their lowest oxygen saturation levels are below 77%.

Original languageEnglish
Pages (from-to)549-553
Number of pages5
JournalInternational Journal of Impotence Research
Volume20
Issue number6
DOIs
Publication statusPublished - 2008 Nov 1
Externally publishedYes

Fingerprint

Obstructive Sleep Apnea
Erectile Dysfunction
Quality of Life
Apnea
Oxygen
Sleep Apnea Syndromes
Referral and Consultation
Sensitivity and Specificity
Control Groups
Incidence

Keywords

  • Erectile dysfunction
  • Obstructive sleep apnea syndrome
  • Quality of life

ASJC Scopus subject areas

  • Urology

Cite this

Erectile dysfunction and disease-specific quality of life in patients with obstructive sleep apnea. / Shin, H. W.; Rah, Yoon Chan; Han, D. H.; Chung, S.; Yoon, I. Y.; Rhee, C. S.; Lee, C. H.; Min, Y. G.; Kim, D. Y.

In: International Journal of Impotence Research, Vol. 20, No. 6, 01.11.2008, p. 549-553.

Research output: Contribution to journalArticle

Shin, H. W. ; Rah, Yoon Chan ; Han, D. H. ; Chung, S. ; Yoon, I. Y. ; Rhee, C. S. ; Lee, C. H. ; Min, Y. G. ; Kim, D. Y. / Erectile dysfunction and disease-specific quality of life in patients with obstructive sleep apnea. In: International Journal of Impotence Research. 2008 ; Vol. 20, No. 6. pp. 549-553.
@article{07ab012008324d88ad7d72bd6c18a0f2,
title = "Erectile dysfunction and disease-specific quality of life in patients with obstructive sleep apnea",
abstract = "Several reports have suggested a high incidence of erectile dysfunction (ED) among patients with obstructive sleep apnea syndrome (OSAS). The aim of this study was to investigate the correlation between OSAS and ED, or disease-specific quality of life (QOL) in patients with OSAS. In addition, we analyzed specific polysomnographic (PSG) parameters in predicting ED in OSAS patients. In total, 32 patients with OSAS and 27 normal controls were asked to complete the Korean versions of the International Index of Erectile Function questionnaire (KIIEF-5) and the Calgary Sleep Apnea Quality of Life Index (SAQLI). All patients then underwent a full-night in-laboratory PSG examination. Patients were diagnosed with OSAS if they had clinical symptoms suggestive of OSAS for at least 1 year and an apnea-hypopnea index (AHI) of more than 10 in PSG. Nineteen patients (59.3{\%}) in the OSAS group showed ED, which was significantly higher than in the control group (8 patients, 29.6{\%}, P=0.012). In addition, SAQLI scores worsened as AHI increased (r=0.327, P=0.011) and as the lowest oxygen saturation level decreased (r=0.420, P=0.001). ED was not significantly correlated with AHI (r=0.061, P=0.649); however, it was significantly correlated with the lowest oxygen saturation decreased (r=0.338, P=0.009). When the cutoff value for the lowest oxygen saturation level to predict ED was set at 77{\%}, its positive predictive value was 88.9{\%} (sensitivity=0.70, specificity=0.62). Thus, all male patients with OSAS should be screened for erectile dysfunction and more comprehensive consultation is needed, especially, if their lowest oxygen saturation levels are below 77{\%}.",
keywords = "Erectile dysfunction, Obstructive sleep apnea syndrome, Quality of life",
author = "Shin, {H. W.} and Rah, {Yoon Chan} and Han, {D. H.} and S. Chung and Yoon, {I. Y.} and Rhee, {C. S.} and Lee, {C. H.} and Min, {Y. G.} and Kim, {D. Y.}",
year = "2008",
month = "11",
day = "1",
doi = "10.1038/ijir.2008.39",
language = "English",
volume = "20",
pages = "549--553",
journal = "International Journal of Impotence Research",
issn = "0955-9930",
publisher = "Nature Publishing Group",
number = "6",

}

TY - JOUR

T1 - Erectile dysfunction and disease-specific quality of life in patients with obstructive sleep apnea

AU - Shin, H. W.

AU - Rah, Yoon Chan

AU - Han, D. H.

AU - Chung, S.

AU - Yoon, I. Y.

AU - Rhee, C. S.

AU - Lee, C. H.

AU - Min, Y. G.

AU - Kim, D. Y.

PY - 2008/11/1

Y1 - 2008/11/1

N2 - Several reports have suggested a high incidence of erectile dysfunction (ED) among patients with obstructive sleep apnea syndrome (OSAS). The aim of this study was to investigate the correlation between OSAS and ED, or disease-specific quality of life (QOL) in patients with OSAS. In addition, we analyzed specific polysomnographic (PSG) parameters in predicting ED in OSAS patients. In total, 32 patients with OSAS and 27 normal controls were asked to complete the Korean versions of the International Index of Erectile Function questionnaire (KIIEF-5) and the Calgary Sleep Apnea Quality of Life Index (SAQLI). All patients then underwent a full-night in-laboratory PSG examination. Patients were diagnosed with OSAS if they had clinical symptoms suggestive of OSAS for at least 1 year and an apnea-hypopnea index (AHI) of more than 10 in PSG. Nineteen patients (59.3%) in the OSAS group showed ED, which was significantly higher than in the control group (8 patients, 29.6%, P=0.012). In addition, SAQLI scores worsened as AHI increased (r=0.327, P=0.011) and as the lowest oxygen saturation level decreased (r=0.420, P=0.001). ED was not significantly correlated with AHI (r=0.061, P=0.649); however, it was significantly correlated with the lowest oxygen saturation decreased (r=0.338, P=0.009). When the cutoff value for the lowest oxygen saturation level to predict ED was set at 77%, its positive predictive value was 88.9% (sensitivity=0.70, specificity=0.62). Thus, all male patients with OSAS should be screened for erectile dysfunction and more comprehensive consultation is needed, especially, if their lowest oxygen saturation levels are below 77%.

AB - Several reports have suggested a high incidence of erectile dysfunction (ED) among patients with obstructive sleep apnea syndrome (OSAS). The aim of this study was to investigate the correlation between OSAS and ED, or disease-specific quality of life (QOL) in patients with OSAS. In addition, we analyzed specific polysomnographic (PSG) parameters in predicting ED in OSAS patients. In total, 32 patients with OSAS and 27 normal controls were asked to complete the Korean versions of the International Index of Erectile Function questionnaire (KIIEF-5) and the Calgary Sleep Apnea Quality of Life Index (SAQLI). All patients then underwent a full-night in-laboratory PSG examination. Patients were diagnosed with OSAS if they had clinical symptoms suggestive of OSAS for at least 1 year and an apnea-hypopnea index (AHI) of more than 10 in PSG. Nineteen patients (59.3%) in the OSAS group showed ED, which was significantly higher than in the control group (8 patients, 29.6%, P=0.012). In addition, SAQLI scores worsened as AHI increased (r=0.327, P=0.011) and as the lowest oxygen saturation level decreased (r=0.420, P=0.001). ED was not significantly correlated with AHI (r=0.061, P=0.649); however, it was significantly correlated with the lowest oxygen saturation decreased (r=0.338, P=0.009). When the cutoff value for the lowest oxygen saturation level to predict ED was set at 77%, its positive predictive value was 88.9% (sensitivity=0.70, specificity=0.62). Thus, all male patients with OSAS should be screened for erectile dysfunction and more comprehensive consultation is needed, especially, if their lowest oxygen saturation levels are below 77%.

KW - Erectile dysfunction

KW - Obstructive sleep apnea syndrome

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=55849098894&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=55849098894&partnerID=8YFLogxK

U2 - 10.1038/ijir.2008.39

DO - 10.1038/ijir.2008.39

M3 - Article

VL - 20

SP - 549

EP - 553

JO - International Journal of Impotence Research

JF - International Journal of Impotence Research

SN - 0955-9930

IS - 6

ER -