Erythrocyte deformability and its hemorheological consideration

Sehyun Shin, Yunhee Ku, Myung Su Park, Jang Soo Suh

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The suspension of hardened erythrocytes (red blood cells) differs from the suspension of normal erythrocytes with respect to their rheological behavior. The deformability of normal and hardened erythrocytes (obtained by heating blood at 49°C or by incubating erythrocytes in a solution of hydrogen peroxide) was measured with a slit diffractometer and erythrocyte suspension viscosity was measured with a rotational viscometer. We found that when erythrocytes were heated at 49°C, with much less deformability than normal erythrocytes, their suspension viscosity was almost the same as the normal blood viscosity at high shear rates, whereas when erythrocytes were incubated in a solution of hydrogen peroxide, with an intermediate decrease of deformability, their suspension viscosity was greatly increased. The present study concluded that not all rigid cells cause an increase in blood viscosity at high shear rates, and therefore that decreased cell deformability is not always a good indicator of high-shear blood viscosity.

Original languageEnglish
Pages (from-to)8349-8353
Number of pages5
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Volume43
Issue number12
DOIs
Publication statusPublished - 2004 Dec 1
Externally publishedYes

Keywords

  • Deformability
  • Erythrocyte
  • Shear rate
  • Tank-tread
  • Viscosity

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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