Estimating 24-hour urine sodium level with spot urine sodium and creatinine

Ho Seok Koo, Yong Chul Kim, Shin Young Ahn, Se Won Oh, Suhnggwon Kim, Ho Jun Chin, Jung Hwan Park

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The 24-hr urine sodium excretion level was estimated based on the spot urine sodium, and the efficacy of the formula was validated to determine the status of low salt intake < 100 mEq Na/day. The 24-hr urine samples were collected from 400 patients. The 24-hr urine creatinine level was estimated with the use of three formulas: a newly derived Korean equation (E24UCR_K), and Tanaka (E24UCR_T) and Cockcroft-Gault (E24UCR_CG) equations. The correlation coefficients between the estimated and measured 24-hr urine creatinine for these three equations were 0.863, 0.846, and 0.896, respectively (All P < 0.001). After estimating the 24-hr urine sodium levels, the correlation coefficients between the estimated and measured 24-hr urine sodium levels were 0.466, 0.490, and 0.516, respectively (All P < 0.001). The sensitivity of three formulas to estimate the measured 24-hr urine sodium ≥100 mEq/day using the estimated amount ≥100 mEq/day was 84.3%, 87.6%, and 84.8%, respectively. In conclusion, the three equations used to estimate the 24-hr urine sodium content were useful to determine the status of low salt intake.

Original languageEnglish
Pages (from-to)S97-S102
JournalJournal of Korean Medical Science
Volume29
DOIs
Publication statusPublished - 2014 Jan 1
Externally publishedYes

Keywords

  • 24-hr urine sodium
  • Spot urine creatinine
  • Spot urine sodium

ASJC Scopus subject areas

  • Medicine(all)

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