TY - JOUR
T1 - Estimating the probability of stroke in Korean hypertensive patients visiting tertiary hospitals using a risk profile from the framingham study
AU - Choi, Cheol Ung
AU - Park, Chang Gyu
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009/4/22
Y1 - 2009/4/22
N2 - Background: Hypertension is the most important single modifiable risk factor for stroke. We investigated the distribution of stroke risk factors and 10-year probability of stroke in Korean hypertensive patients. Methods: A total of 1,402 hypertensive patients treated by cardiology departments at 37 general hospitals nationwide were enrolled. Risk factors for stroke were evaluated using a series of laboratory tests and physical examinations, and the 10-year probability of stroke was determined by applying the Framingham stroke risk equation. Results: The proportion of patients who have uncontrolled hypertension despite use of antihypertensives was 37.2% (37.2% women, 37.3% men, p = 0.990). The average 10-year probability of stroke in hypertensive patients was 24.27% (24.17% women, 24.39% men, p = 0.825), approximately 2.4 times higher than of the risk of stroke observed in the Korean Cancer Prevention Study [KCPS] cohort. The 10-year stroke probability in patients with hypertension increased in proportion to age. In patients for hypertension, the 10-year probability of stroke increased in proportion to blood pressure. Conclusion: Aggressive interventions are mandated to reduce blood pressure and alleviate the high risk of stroke in hypertensive patients.
AB - Background: Hypertension is the most important single modifiable risk factor for stroke. We investigated the distribution of stroke risk factors and 10-year probability of stroke in Korean hypertensive patients. Methods: A total of 1,402 hypertensive patients treated by cardiology departments at 37 general hospitals nationwide were enrolled. Risk factors for stroke were evaluated using a series of laboratory tests and physical examinations, and the 10-year probability of stroke was determined by applying the Framingham stroke risk equation. Results: The proportion of patients who have uncontrolled hypertension despite use of antihypertensives was 37.2% (37.2% women, 37.3% men, p = 0.990). The average 10-year probability of stroke in hypertensive patients was 24.27% (24.17% women, 24.39% men, p = 0.825), approximately 2.4 times higher than of the risk of stroke observed in the Korean Cancer Prevention Study [KCPS] cohort. The 10-year stroke probability in patients with hypertension increased in proportion to age. In patients for hypertension, the 10-year probability of stroke increased in proportion to blood pressure. Conclusion: Aggressive interventions are mandated to reduce blood pressure and alleviate the high risk of stroke in hypertensive patients.
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U2 - 10.1186/1471-2377-9-16
DO - 10.1186/1471-2377-9-16
M3 - Article
C2 - 19386109
AN - SCOPUS:65549128836
VL - 9
JO - BMC Neurology
JF - BMC Neurology
SN - 1471-2377
M1 - 16
ER -