Estimation of directional coupling between cortical areas using Near-Infrared Spectroscopy (NIRS)

Chang Hwan Im; Young Jin Jung; Seungduk Lee; Dalkwon Koh; Do Won Kim; Beop Min Kim

doi:10.1364/OE.18.005730

Estimation of directional coupling between cortical areas using Near-Infrared Spectroscopy (NIRS)

Chang Hwan Im, Young Jin Jung, Seungduk Lee, Dalkwon Koh, Do Won Kim, Beop Min Kim

School of Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

This study invesitigated the feasibility of measuring directional coupling between cortical areas with near-infrared spectroscopy (NIRS). Cerebral hemodynamic responses were recorded at the primary somatosensory cortex (S1), secondary somatosensory cortex (S2), and primary motor cortex (M1) regions of the rat barrel cortex during electrical stimulation of rat whiskers. Deoxyhemoglobin concentration changes were calculated from NIRS recordings and the Granger causality based on the multivariate autoregressive (MVAR) model was used to estimate the effective causal connectivity among S1, S2, and M1. The estimated causality patterns of seven rats showed consistent unidirectional coupling between the somatosensory areas and the motor areas (S1 and S2 → M1), which coincided well with our hypothesis because the rats' motor function was completely anesthetized. Our preliminary results suggest that corticocortical directional coupling can be successfully investigated with NIRS

Original language	English
Pages (from-to)	5730-5739
Number of pages	10
Journal	Optics Express
Volume	18
Issue number	6
DOIs	https://doi.org/10.1364/OE.18.005730
Publication status	Published - 2010 Mar 15

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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abstract = "This study invesitigated the feasibility of measuring directional coupling between cortical areas with near-infrared spectroscopy (NIRS). Cerebral hemodynamic responses were recorded at the primary somatosensory cortex (S1), secondary somatosensory cortex (S2), and primary motor cortex (M1) regions of the rat barrel cortex during electrical stimulation of rat whiskers. Deoxyhemoglobin concentration changes were calculated from NIRS recordings and the Granger causality based on the multivariate autoregressive (MVAR) model was used to estimate the effective causal connectivity among S1, S2, and M1. The estimated causality patterns of seven rats showed consistent unidirectional coupling between the somatosensory areas and the motor areas (S1 and S2 → M1), which coincided well with our hypothesis because the rats' motor function was completely anesthetized. Our preliminary results suggest that corticocortical directional coupling can be successfully investigated with NIRS",

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AU - Im, Chang Hwan

AU - Jung, Young Jin

AU - Lee, Seungduk

AU - Koh, Dalkwon

AU - Kim, Do Won

AU - Kim, Beop Min

PY - 2010/3/15

Y1 - 2010/3/15

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Estimation of directional coupling between cortical areas using Near-Infrared Spectroscopy (NIRS)

Abstract

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