Evaluation of four rapid diagnostic tests for the diagnosis of Plasmodium vivax in Korea

Kyung Hee Kim, Jin Woo Jang, Mi Kyung Woo, Jun Seo Oh, Eun Taek Han, Won Ja Lee, Seong Soo A An, Chae Seung Lim

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9 Citations (Scopus)

Abstract

Objective To evaluate 4 rapid malaria diagnostic kits (RDTs) in Korea: OptiMAL test, SD BIOLINE Malaria Ag P.f/Pan test, Humasis Malaria P.f/Pan antigen test and CareStart™ Malaria Pf/Pv Combo test. Methods Hundred malaria patients with Plasmodium vivax (P. vivax) and 100 healthy volunteers were recruited. The results from earlier four RDTs were compared with the reference standard, the Giemsa-stained traditional microscopic diagnosis. Results Compared with the reference standard, the sensitivity and specificity for Plasmodium vivax were 92.7 and 100% for SD BIOLINE Malaria Ag P.f/Pan; and 94.6% and 100% for OptiMAL; 95.5% and 100% for both Humasis Malaria P.f/Pan antigen test and CareStart™ Malaria Pf/Pv Combo test. Conclusion The performances of all four malaria RDT kits were acceptable, although Humasis Malaria P.f/Pan antigen test and CareStartTM Malaria Pf/Pv Combo test gave superior performances with ROK isolates.

Original languageEnglish
Pages (from-to)1427-1431
Number of pages5
JournalTropical Medicine and International Health
Volume16
Issue number11
DOIs
Publication statusPublished - 2011 Nov 1

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Keywords

  • CareStart
  • OptiMAL
  • Plasmodium vivax
  • Sensitivity
  • Specificity

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Parasitology

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