Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes

So Young Huh, Su Hyun Kim, Woojun Kim, Sang Hyun Lee, Min Su Park, Suk Won Ahn, Byung Jo Kim, Joong Yang Cho, Ho Jin Kim

    Research output: Contribution to journalArticlepeer-review

    11 Citations (Scopus)

    Abstract

    We investigated the validity of the 2005 and 2010 McDonald magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) to predict the conversion of clinically definite multiple sclerosis (CDMS) in 94 Korean patients with clinically isolated syndromes (CIS). The sensitivity, specificity, accuracy, positive and negative predictive values of the 2005, 2010 McDonald DIS criteria were comparable to those observed in the Caucasian population. This finding suggests that after careful exclusion of alternative explanations, particularly neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD), both the 2005 and 2010 McDonald DIS criteria are also useful to predict conversion to CDMS in Korean patients with CIS.

    Original languageEnglish
    Pages (from-to)492-495
    Number of pages4
    JournalMultiple Sclerosis Journal
    Volume20
    Issue number4
    DOIs
    Publication statusPublished - 2014 Apr

    Keywords

    • MRI
    • Multiple sclerosis

    ASJC Scopus subject areas

    • Neurology
    • Clinical Neurology

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