Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes

So Young Huh; Su Hyun Kim; Woojun Kim; Sang Hyun Lee; Min Su Park; Suk Won Ahn; Byung Jo Kim; Joong Yang Cho; Ho Jin Kim

doi:10.1177/1352458513496881

Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes

So Young Huh, Su Hyun Kim, Woojun Kim, Sang Hyun Lee, Min Su Park, Suk Won Ahn, Byung Jo Kim, Joong Yang Cho, Ho Jin Kim

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

We investigated the validity of the 2005 and 2010 McDonald magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) to predict the conversion of clinically definite multiple sclerosis (CDMS) in 94 Korean patients with clinically isolated syndromes (CIS). The sensitivity, specificity, accuracy, positive and negative predictive values of the 2005, 2010 McDonald DIS criteria were comparable to those observed in the Caucasian population. This finding suggests that after careful exclusion of alternative explanations, particularly neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD), both the 2005 and 2010 McDonald DIS criteria are also useful to predict conversion to CDMS in Korean patients with CIS.

Original language	English
Pages (from-to)	492-495
Number of pages	4
Journal	Multiple Sclerosis Journal
Volume	20
Issue number	4
DOIs	https://doi.org/10.1177/1352458513496881
Publication status	Published - 2014 Apr

Keywords

MRI
Multiple sclerosis

ASJC Scopus subject areas

Neurology
Clinical Neurology

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title = "Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes",

abstract = "We investigated the validity of the 2005 and 2010 McDonald magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) to predict the conversion of clinically definite multiple sclerosis (CDMS) in 94 Korean patients with clinically isolated syndromes (CIS). The sensitivity, specificity, accuracy, positive and negative predictive values of the 2005, 2010 McDonald DIS criteria were comparable to those observed in the Caucasian population. This finding suggests that after careful exclusion of alternative explanations, particularly neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD), both the 2005 and 2010 McDonald DIS criteria are also useful to predict conversion to CDMS in Korean patients with CIS.",

keywords = "MRI, Multiple sclerosis",

author = "Huh, {So Young} and Kim, {Su Hyun} and Woojun Kim and Lee, {Sang Hyun} and Park, {Min Su} and Ahn, {Suk Won} and Kim, {Byung Jo} and Cho, {Joong Yang} and Kim, {Ho Jin}",

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AU - Huh, So Young

AU - Kim, Su Hyun

AU - Kim, Woojun

AU - Lee, Sang Hyun

AU - Park, Min Su

AU - Ahn, Suk Won

AU - Kim, Byung Jo

AU - Cho, Joong Yang

AU - Kim, Ho Jin

PY - 2014/4

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AB - We investigated the validity of the 2005 and 2010 McDonald magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) to predict the conversion of clinically definite multiple sclerosis (CDMS) in 94 Korean patients with clinically isolated syndromes (CIS). The sensitivity, specificity, accuracy, positive and negative predictive values of the 2005, 2010 McDonald DIS criteria were comparable to those observed in the Caucasian population. This finding suggests that after careful exclusion of alternative explanations, particularly neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD), both the 2005 and 2010 McDonald DIS criteria are also useful to predict conversion to CDMS in Korean patients with CIS.

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Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes

Abstract

Keywords

ASJC Scopus subject areas

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