Exploiting the natural metabolic diversity of Streptomyces venezuelae to generate unusual reduced macrolides

Je Won Park, Hong Se Oh, Won Seok Jung, Sung Ryeol Park, Ah Reum Han, Yeon Hee Ban, Eun Ji Kim, Han Young Kang, Yeo Joon Yoon

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

An unusual set of reduced macrolide antibiotics was discovered by combination of organic synthesis and a biosynthetic approach using the unique metabolic diversity of Streptomyces venezuelae; two unnatural 16-membered ring macrolides are also created by employing this bio-catalyst.

Original languageEnglish
Pages (from-to)5782-5784
Number of pages3
JournalChemical Communications
Issue number44
DOIs
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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  • Cite this

    Park, J. W., Oh, H. S., Jung, W. S., Park, S. R., Han, A. R., Ban, Y. H., Kim, E. J., Kang, H. Y., & Yoon, Y. J. (2008). Exploiting the natural metabolic diversity of Streptomyces venezuelae to generate unusual reduced macrolides. Chemical Communications, (44), 5782-5784. https://doi.org/10.1039/b814603a