Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace

Hyung Il Moon; Saemi Shin; Sang Hoon Byeon

doi:10.1080/10807039.2014.926203

Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace

Hyung Il Moon, Saemi Shin, Sang Hoon Byeon

School of Health and Environmental Science

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m³, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m³, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.

Original language	English
Pages (from-to)	744-752
Number of pages	9
Journal	Human and Ecological Risk Assessment
Volume	21
Issue number	3
DOIs	https://doi.org/10.1080/10807039.2014.926203
Publication status	Published - 2015 Apr 3

Keywords

1-bromopropane
Monte Carlo simulation
point of departure
reference concentration
risk assessment

ASJC Scopus subject areas

Ecological Modelling
Pollution
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/10807039.2014.926203

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title = "Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace",

abstract = "ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m3, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m3, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.",

keywords = "1-bromopropane, Monte Carlo simulation, point of departure, reference concentration, risk assessment",

author = "Moon, {Hyung Il} and Saemi Shin and Byeon, {Sang Hoon}",

note = "Funding Information: This work was supported by the Korea Occupational Safety and Health Agency and a research grant from Korea University. Publisher Copyright: {\textcopyright} 2015, Copyright {\textcopyright} Taylor & Francis Group, LLC.",

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doi = "10.1080/10807039.2014.926203",

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AU - Moon, Hyung Il

AU - Shin, Saemi

AU - Byeon, Sang Hoon

N1 - Funding Information: This work was supported by the Korea Occupational Safety and Health Agency and a research grant from Korea University. Publisher Copyright: © 2015, Copyright © Taylor & Francis Group, LLC.

PY - 2015/4/3

Y1 - 2015/4/3

N2 - ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m3, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m3, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.

AB - ABSTRACT: This study was conducted to estimate the health risk to workers exposed to 1-bromopropane (1-BP) used as a cleaning solvent in their workplaces. Fifty samples from 10 workplaces that use 1-BP as a cleaning solvent were obtained to assess 1-BP concentrations. An exposure assessment revealed central tendency exposure (CTE) and reasonable maximum exposure (RME) levels of 82.1 and 214.8 mg/m3, respectively. For risk characterization, the 1-BP exposure concentrations for reproductive and developmental toxicities were calculated as 2.8 and 8.5 mg/m3, respectively, and compared with the reference concentrations in the workplace. The CTE and RME hazard quotients (HQ) were, respectively, 29.4 and 77.0 for reproductive toxicity and 9.6 and 25.2 for developmental toxicity. The results of our 1-BP risk assessment indicated that the CTE-HQs for both categories were higher than the acceptable risk value of 1, indicating that 1-BP may be considered as harmful to workers.

KW - 1-bromopropane

KW - Monte Carlo simulation

KW - point of departure

KW - reference concentration

KW - risk assessment

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Exposure Monitoring and Health Risk Assessment of 1-Bromopropane as a Cleaning Solvent in the Workplace

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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