Eye tracking and gating system for proton therapy of orbital tumors

Dongho Shin, Seung Hoon Yoo, Sung Ho Moon, Myonggeun Yoon, Se Byeong Lee, Sung Yong Park

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Purpose: A new motion-based gated proton therapy for the treatment of orbital tumors using real-time eye-tracking system was designed and evaluated. Methods: We developed our system by image-pattern matching, using a normalized cross-correlation technique with LabVIEW 8.6 and Vision Assistant 8.6 (National Instruments, Austin, TX). To measure the pixel spacing of an image consistently, four different calibration modes such as the point-detection, the edge-detection, the line-measurement, and the manual measurement mode were suggested and used. After these methods were applied to proton therapy, gating was performed, and radiation dose distributions were evaluated. Results: Moving phantom verification measurements resulted in errors of less than 0.1 mm for given ranges of translation. Dosimetric evaluation of the beam-gating system versus nongated treatment delivery with a moving phantom shows that while there was only 0.83 mm growth in lateral penumbra for gated radiotherapy, there was 4.95 mm growth in lateral penumbra in case of nongated exposure. The analysis from clinical results suggests that the average of eye movements depends distinctively on each patient by showing 0.44 mm, 0.45 mm, and 0.86 mm for three patients, respectively. Conclusions: The developed automatic eye-tracking based beam-gating system enabled us to perform high-precision proton radiotherapy of orbital tumors.

Original languageEnglish
Pages (from-to)4265-4273
Number of pages9
JournalMedical physics
Issue number7
Publication statusPublished - 2012 Jul


  • eye tracking
  • orbital tumors
  • proton
  • proton gating

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging


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